Protein Info for MPMX19_06542 in Azospirillum sp. SherDot2

Annotation: Putative multidrug export ATP-binding/permease protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 601 transmembrane" amino acids 7 to 27 (21 residues), see Phobius details amino acids 62 to 80 (19 residues), see Phobius details amino acids 139 to 159 (21 residues), see Phobius details amino acids 164 to 184 (21 residues), see Phobius details amino acids 249 to 270 (22 residues), see Phobius details amino acids 280 to 299 (20 residues), see Phobius details PF00664: ABC_membrane" amino acids 47 to 292 (246 residues), 61.1 bits, see alignment E=1.4e-20 PF00005: ABC_tran" amino acids 364 to 512 (149 residues), 108.6 bits, see alignment E=4.1e-35

Best Hits

KEGG orthology group: K06147, ATP-binding cassette, subfamily B, bacterial (inferred from 91% identity to azl:AZL_f00030)

Predicted SEED Role

"Lipid A export ATP-binding/permease protein MsbA" in subsystem ZZ gjo need homes

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (601 amino acids)

>MPMX19_06542 Putative multidrug export ATP-binding/permease protein (Azospirillum sp. SherDot2)
MFVRDGFLGRAILLNLAAAGGIGLMGLEPVAMRGLVDALTGISGAGLSGNHPSGSPAWTA
EVMRWFLLLGGLWIASALFNRLRELVDMHTSPALRHAIQVRLFDHLIDHSPRYFQDNFAG
NLGQKVKQAGQSAIQILEILTNDIIRIVIILAIGLTLLASAQPLFAGLLVGWTVAHLALS
ALLARRCLRLSHAFSEEVSSTTGRMVDIIANAELVRAFARRRQELAGLSDALTGEIDRSK
ELRWFLTKMWFWLFNALLVFQIVLIGLAVSQATAGRMSIGEFAMIFSLASIVGTNVWGLS
TRMLGFFEQLGVLSGALDLIVRPHEIPDPPGRPDLTVGDGAIRFEDIRFAHPGSDPETGG
AVFDGLSLTIRPGERVALVGPSGAGKSTLVRLLRRQFPLQGGRILIDGQDIAAVSLASLN
RAVAEVPQLPSLFHRSIRDNIAYGSEGASDEAIRAASARAHCDRFIEGRAAGYDTVVGER
GIQLSGGERQRVAIARAFLKDAPVLVLDEATSSLDSETEHLIQDALLGLFEGRTVIAIAH
RLSTVTGMDRILYMEKGRILEDGDHATLLRRDGPYARLWRRQVGGFLPDDAGSITDMEEA
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