Protein Info for MPMX19_06517 in Azospirillum sp. SherDot2
Annotation: Vitamin B12 import ATP-binding protein BtuD
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 62% identical to METN2_PSEF5: Methionine import ATP-binding protein MetN 2 (metN2) from Pseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5)
KEGG orthology group: K02071, D-methionine transport system ATP-binding protein (inferred from 95% identity to azl:AZL_a01160)Predicted SEED Role
"Methionine ABC transporter ATP-binding protein" in subsystem Methionine Biosynthesis or Methionine Degradation
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (372 amino acids)
>MPMX19_06517 Vitamin B12 import ATP-binding protein BtuD (Azospirillum sp. SherDot2) MLWKRATAHMAGHAAAANPAPTALPDPSSPHILFDGVRKTYPGGVEALQTVSFAIPRGSV FGIIGRSGAGKSTLLRAINMLERPSGGRVLVDGIDVGGLGEEDLVRLRRRIGMIFQHFNL LSAKTVRENVGLPLKVAGVAAAEIRRRVDELLDLVGLADKADVYPSKLSGGQKQRVGIAR ALVHRPEILLCDEATSALDPETTHAILGLLRDINAKLGLTIVLITHDMAVIRAICDEVMV LDRGHRVEHGPVWSVFGTPQGDATRALLRPLQHGLPDDIARRLQADPPKQGGGQAVLSLR FTGESHPEGISLASLLALAPDAKLLHGGIDRIQGHAQGDLVIAVPVAAMRSAAGARFSPD SWKVLGYVADDV