Protein Info for MPMX19_06408 in Azospirillum sp. SherDot2

Annotation: Cation efflux system protein CusB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 465 signal peptide" amino acids 1 to 31 (31 residues), see Phobius details TIGR01730: efflux transporter, RND family, MFP subunit" amino acids 157 to 441 (285 residues), 99.6 bits, see alignment E=8.6e-33 PF16576: HlyD_D23" amino acids 161 to 368 (208 residues), 270.3 bits, see alignment E=1.8e-84 PF16572: HlyD_D4" amino acids 207 to 258 (52 residues), 34 bits, see alignment 4.2e-12 PF00529: CusB_dom_1" amino acids 238 to 436 (199 residues), 32.9 bits, see alignment E=1e-11 PF13437: HlyD_3" amino acids 266 to 364 (99 residues), 56.3 bits, see alignment E=9.7e-19

Best Hits

Predicted SEED Role

"Probable Co/Zn/Cd efflux system membrane fusion protein" in subsystem Cobalt-zinc-cadmium resistance

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (465 amino acids)

>MPMX19_06408 Cation efflux system protein CusB (Azospirillum sp. SherDot2)
MNRSPALLVVLMAGTIVAGMPAFAQSSAGASHAGHGAPAAAQPAGAGKVLYYRNPMGLPD
TSPVPKRDSMGMEYVPVYEGEAAPVSVAAPAQNPAGPRKILYYRNPMGLPDTSAVPKKDP
MGMDYVPVYEGEDSASGTVTISSDKVQKLGVRTDAAMRRAISRQVRAVGTVQVDERRLFV
VAPKFEAWIERLLVDTTGDTVRKGQPLMEVYSPELVLAQQEYLVARQGGAQLAEASLQRL
RNLDVPEEEIDRLRKTGKASRTLTYRAAAGGVVLEKSAVRGMRFMPGEALYRIADLTHVW
LVADVFEQDLGYVKPGQDVDVTVNSLPGKTFTGKVSFVYPTLTAESRTGKVRVELPNADG
LLKPNLYATVHLNADLGAMARLAVPDSALLDTGKRQAVLVEIGEGRYEPRDVKAGARADG
YVQILAGLEEGERVVVRANFLIDSESNLRAALSAFGGSGGQHQQH