Protein Info for MPMX19_06176 in Azospirillum sp. SherDot2

Annotation: Cytochrome bo(3) ubiquinol oxidase subunit 1

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 665 transmembrane" amino acids 24 to 46 (23 residues), see Phobius details amino acids 67 to 87 (21 residues), see Phobius details amino acids 111 to 134 (24 residues), see Phobius details amino acids 152 to 174 (23 residues), see Phobius details amino acids 197 to 221 (25 residues), see Phobius details amino acids 239 to 262 (24 residues), see Phobius details amino acids 283 to 306 (24 residues), see Phobius details amino acids 318 to 340 (23 residues), see Phobius details amino acids 354 to 376 (23 residues), see Phobius details amino acids 389 to 411 (23 residues), see Phobius details amino acids 423 to 447 (25 residues), see Phobius details amino acids 463 to 483 (21 residues), see Phobius details amino acids 501 to 525 (25 residues), see Phobius details amino acids 597 to 634 (38 residues), see Phobius details TIGR02843: cytochrome o ubiquinol oxidase, subunit I" amino acids 10 to 654 (645 residues), 1124.8 bits, see alignment E=0 PF00115: COX1" amino acids 64 to 512 (449 residues), 495.5 bits, see alignment E=7.2e-153

Best Hits

Swiss-Prot: 68% identical to CYOB_ECOLI: Cytochrome bo(3) ubiquinol oxidase subunit 1 (cyoB) from Escherichia coli (strain K12)

KEGG orthology group: K02298, cytochrome o ubiquinol oxidase subunit I [EC: 1.10.3.-] (inferred from 98% identity to azl:AZL_e01320)

MetaCyc: 68% identical to cytochrome bo3 subunit 1 (Escherichia coli K-12 substr. MG1655)
RXN-21817 [EC: 7.1.1.3]

Predicted SEED Role

"Cytochrome O ubiquinol oxidase subunit I (EC 1.10.3.-)" in subsystem Terminal cytochrome O ubiquinol oxidase or Terminal cytochrome oxidases (EC 1.10.3.-)

MetaCyc Pathways

Isozymes

Compare fitness of predicted isozymes for: 1.10.3.-

Use Curated BLAST to search for 1.10.3.- or 7.1.1.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (665 amino acids)

>MPMX19_06176 Cytochrome bo(3) ubiquinol oxidase subunit 1 (Azospirillum sp. SherDot2)
MLETLTTFLFGRLSLESFPYHEPIVVATFFAVMLGGIALVAALSYFKLWGYLWKEWFTTV
DHKRIGIMYMILGLIMLLRGFADAIMMRAQQAMAFNGSEGYLNSHHFDQVFTAHGVIMIF
FVAMPFVTGLMNYVVPLQIGARDVSFPFLNNFSFWMTVGGAVLIMASLFIGEFARTGWLA
YPPLSGLEASPDVGVDYYIWALQVAGVGTTLSGINLICTIVKMRAPGMTMMKMPVFTWTS
LCTNVLIVASFPILTAVLVLLSLDRYAGTHFFTNDMGGNPMMYVNLIWIWGHPEVYILIL
PCFGIFSEVTSTFTGKKLFGYTSMVYATVVITILSYLVWLHHFFTMGSGASVNSFFGITT
MIISIPTGAKIFNWLFTMYRGRIRFELPMMWTIAFMLTFVLGGMTGVLLAVPPADFVLHN
SLFLIAHFHNVIIGGVLFGLFAGIYYWWPKAFGFRLDPFWGKMSFWFWVIGFYFAFMPLY
VLGLMGVTRRLRVFEDPSLQIWFQIAAFGAVLIALGIGSFLIQIAVSILKRKQLVDVSGD
PWHGRTLEWATSSPPPDYNFAFTPVIHDNDAWWDMKKRGYARPLEGFRPIHMPSNTGTGI
ILAGLSTVLGFALIWHIWWLAAVSFVGLLAVAINHTFNYNRDFHIPVDEVVRTESERTRL
LSGQV