Protein Info for MPMX19_06141 in Azospirillum sp. SherDot2

Annotation: Intermembrane phospholipid transport system permease protein MlaE

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 258 signal peptide" amino acids 1 to 33 (33 residues), see Phobius details transmembrane" amino acids 50 to 70 (21 residues), see Phobius details amino acids 147 to 176 (30 residues), see Phobius details amino acids 196 to 217 (22 residues), see Phobius details amino acids 228 to 255 (28 residues), see Phobius details TIGR00056: ABC transport permease subunit" amino acids 22 to 255 (234 residues), 254.4 bits, see alignment E=7.1e-80 PF02405: MlaE" amino acids 42 to 251 (210 residues), 276.5 bits, see alignment E=7.3e-87

Best Hits

Swiss-Prot: 62% identical to Y080_RICFE: Probable ABC transporter permease protein RF_0080 (RF_0080) from Rickettsia felis (strain ATCC VR-1525 / URRWXCal2)

KEGG orthology group: K02066, putative ABC transport system permease protein (inferred from 100% identity to azl:AZL_e01710)

Predicted SEED Role

"ABC-type transport system involved in resistance to organic solvents"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (258 amino acids)

>MPMX19_06141 Intermembrane phospholipid transport system permease protein MlaE (Azospirillum sp. SherDot2)
MGFLAATGRAFLIFLEATGRLALFTGSALSHCVRPPLYPRQILRQMIDIGYYSLPVVGLT
ALFTGMVLALQSYSGFSRFQAEGAIATVVVLSITRELGPVLAGLMVAGRIGAAMAAEIGT
MRVTEQIDALSTLSTNPYKYLVAPRLIAGLTMVPLLVIVADIIGVFGGFLVGVYRLDFNA
ASYINRTWEFLQPVDVISGLVKAAIFGFLIALMGCYHGYHSKGGAQGVGAATTNAVVSAS
IMILVWNYLITGLFFSTK