Protein Info for MPMX19_06037 in Azospirillum sp. SherDot2

Annotation: Tetracycline resistance protein, class C

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 414 transmembrane" amino acids 12 to 35 (24 residues), see Phobius details amino acids 48 to 68 (21 residues), see Phobius details amino acids 80 to 98 (19 residues), see Phobius details amino acids 104 to 125 (22 residues), see Phobius details amino acids 137 to 159 (23 residues), see Phobius details amino acids 167 to 186 (20 residues), see Phobius details amino acids 221 to 244 (24 residues), see Phobius details amino acids 254 to 273 (20 residues), see Phobius details amino acids 285 to 303 (19 residues), see Phobius details amino acids 309 to 327 (19 residues), see Phobius details amino acids 347 to 367 (21 residues), see Phobius details amino acids 379 to 400 (22 residues), see Phobius details PF07690: MFS_1" amino acids 15 to 358 (344 residues), 175.9 bits, see alignment E=1.7e-55 PF00083: Sugar_tr" amino acids 24 to 189 (166 residues), 43.3 bits, see alignment E=3.8e-15 PF12832: MFS_1_like" amino acids 46 to 160 (115 residues), 32 bits, see alignment E=1.1e-11

Best Hits

Swiss-Prot: 41% identical to TCR3_ECOLX: Tetracycline resistance protein, class C (tetA) from Escherichia coli

KEGG orthology group: K08151, MFS transporter, DHA1 family, tetracycline resistance protein (inferred from 90% identity to azl:AZL_e02360)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (414 amino acids)

>MPMX19_06037 Tetracycline resistance protein, class C (Azospirillum sp. SherDot2)
MSSVRPRKAAIAFILVTAALDIVAMGIVIPVLPALIEEFAGADAQAGTINGALVALWALM
QFFSSPVIGSLSDRFGRRPVILLSALGLAADYVLMAVAPNLWWLVLGRAVAGITSSSFTT
VFAYMADVTPPEQRARAYGLIGAAFSAGFIAGPLLGGVLGEISPRAPFWGAGLLSGLAFL
YGLAVLPESLPQESRMAFSWRRANPFGAFQLLRSHPELSGLAMVNFMLHVSHQVFPAVFV
LYAAHRYGWSAWDVGLLLSMVGALDMLVQGLVVSRVVKWLGDRGTMIVGLFGGAVGLACM
GLAPDGGWFAFAIVPNALWGLAMPTIQSLMTQRVGSSEQGQLQGANMSVASVAGILSPVF
FGTVYSASVGIDPLFPHPGAAFLIAALVMLAGAVIGWVVARRNGRAGEAGGVAA