Protein Info for MPMX19_06022 in Azospirillum sp. SherDot2

Annotation: Bicyclomycin resistance protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 408 transmembrane" amino acids 16 to 34 (19 residues), see Phobius details amino acids 56 to 76 (21 residues), see Phobius details amino acids 84 to 104 (21 residues), see Phobius details amino acids 110 to 131 (22 residues), see Phobius details amino acids 143 to 167 (25 residues), see Phobius details amino acids 173 to 192 (20 residues), see Phobius details amino acids 222 to 246 (25 residues), see Phobius details amino acids 258 to 275 (18 residues), see Phobius details amino acids 287 to 310 (24 residues), see Phobius details amino acids 315 to 337 (23 residues), see Phobius details amino acids 349 to 371 (23 residues), see Phobius details amino acids 378 to 399 (22 residues), see Phobius details TIGR00710: drug resistance transporter, Bcr/CflA subfamily" amino acids 19 to 393 (375 residues), 332.3 bits, see alignment E=2.8e-103 PF07690: MFS_1" amino acids 28 to 365 (338 residues), 166 bits, see alignment E=1.1e-52 PF00083: Sugar_tr" amino acids 52 to 195 (144 residues), 36.2 bits, see alignment E=3.4e-13

Best Hits

KEGG orthology group: K07552, MFS transporter, DHA1 family, bicyclomycin/chloramphenicol resistance protein (inferred from 91% identity to azl:AZL_e02530)

Predicted SEED Role

"Multidrug resistance transporter, Bcr/CflA family" in subsystem Copper homeostasis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (408 amino acids)

>MPMX19_06022 Bicyclomycin resistance protein (Azospirillum sp. SherDot2)
MLARLAAVRSRSPAESPFFIAALGVLMSFGPMGTDMYLPGMPAIGRDLHAAQDQVQWTLS
AFFLGFGVGQLLWGALSDRFGRRIPVATGILLYAIGCVGCSMTVDVGHLAAWRFVQAVGA
CAGPVLVRAMIRDVFERDRAASVLSMMMLVMGAAPIIAPLIGGQILVWANWRWIFWAQAA
FGIVALLALASLPETHPDSRRTSLRPMVLGEAYRKLLTDRRYLGYAVGSSFIYAGMFAFI
SGSPFVYIELFGVRPENYGFLFGLNIVGMIIVNTLNSRAVMRFGSDVMLRIGVWLAAATG
ILLVACVLGGWGGLWGLVGCLFLFMSVTGFCFANSMAGALQSFPQMAGTASALAGMLQFS
TGALSGWAVGLMADGTAMPMAGVIGGAALVSLALNLWLIRPVRRRLPA