Protein Info for MPMX19_05980 in Azospirillum sp. SherDot2

Annotation: 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 206 PF13489: Methyltransf_23" amino acids 25 to 163 (139 residues), 47.3 bits, see alignment E=6.9e-16 PF01135: PCMT" amino acids 31 to 119 (89 residues), 23.1 bits, see alignment E=2e-08 PF01209: Ubie_methyltran" amino acids 34 to 159 (126 residues), 59.2 bits, see alignment E=1.4e-19 PF13847: Methyltransf_31" amino acids 40 to 144 (105 residues), 61 bits, see alignment E=4.1e-20 PF13649: Methyltransf_25" amino acids 44 to 137 (94 residues), 72.1 bits, see alignment E=1.8e-23 PF08241: Methyltransf_11" amino acids 45 to 141 (97 residues), 81.3 bits, see alignment E=2.4e-26 PF08242: Methyltransf_12" amino acids 45 to 138 (94 residues), 54.4 bits, see alignment E=6.3e-18

Best Hits

Swiss-Prot: 43% identical to PMTA_RHOSH: Phosphatidylethanolamine N-methyltransferase (pmtA) from Rhodobacter sphaeroides

KEGG orthology group: None (inferred from 94% identity to azl:AZL_e02950)

Predicted SEED Role

"Phosphatidylethanolamine N-methyltransferase (EC 2.1.1.17)" (EC 2.1.1.17)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.1.1.17

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (206 amino acids)

>MPMX19_05980 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial (Azospirillum sp. SherDot2)
MDAESIRAAYRRYAGFYDRVFGVLLASGRHAAVEWLNRRGGLRILEVGVGTGLSLSDYRK
DNRVVGIDLSTDMLKVAQERVEREKLDHVEGLLEMDAGKLAFADGSFDVVVAMYVMTVVP
DPQGTMAELERVCKPGGDIVIVNHFAAPEAGVRRAVEGWLSPLSKKLGWRPDFTLDAMMT
GSRLAVESIRTLPPFGLFSLLHCRRG