Protein Info for MPMX19_05963 in Azospirillum sp. SherDot2

Annotation: UvrABC system protein C

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 629 TIGR00194: excinuclease ABC subunit C" amino acids 15 to 607 (593 residues), 456.4 bits, see alignment E=7.9e-141 PF01541: GIY-YIG" amino acids 24 to 93 (70 residues), 30.9 bits, see alignment E=5.7e-11 PF02151: UVR" amino acids 234 to 256 (23 residues), 22.9 bits, see alignment (E = 1.1e-08) PF08459: UvrC_RNaseH_dom" amino acids 403 to 561 (159 residues), 159.6 bits, see alignment E=1.1e-50 PF14520: HHH_5" amino acids 578 to 626 (49 residues), 40.1 bits, see alignment 8.3e-14

Best Hits

Swiss-Prot: 52% identical to UVRC_GLUOX: UvrABC system protein C (uvrC) from Gluconobacter oxydans (strain 621H)

KEGG orthology group: K03703, excinuclease ABC subunit C (inferred from 60% identity to rce:RC1_1885)

Predicted SEED Role

"Excinuclease ABC subunit C" in subsystem DNA repair, UvrABC system

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (629 amino acids)

>MPMX19_05963 UvrABC system protein C (Azospirillum sp. SherDot2)
MDGVPGSGADVIRAQLPTLPDTPGVYRMLAADGSVLYVGKAKNLKRRVASYTRTDGLPNR
TRRMVSLTRSMEFVTTHTEAEALLLEANLIRSLLPPFNILVKDDRSFSYIVIGQSNKRGG
HDFPRLMHHRGSAERRGTSGKGNRRESDLFGPYASPHLVGMTIAALQRAFLLRTCDDGVF
ASRTRPCLQHQIKRCSAPCVGRVDEEDYAAQVQGVRDVLSGRSAEVQAEFARHMLDSSDR
LEYEDAARWRDRIRALTALQSRQDINLEDTLGDADVLALHRDGGAACVQAFFFRGGRNQG
TRAFFPRVDAEEEPGDILAAFAAQLYADTPPPGLLLLSEPVESAELLEEALSLSAGHHVA
VECPKRGPKRRAVEHAQTNARDALGRRLAERSTQATLLEGVARVFGLPDAPRRVEIYDTS
HIQGSFPVGAMVVAGPEGFQRNAYRRFYIRDPEAAGNDYAMLRETFTRRFHRSSDAGRDS
GQWPDLVLIDGGLGQLNAVKDELAMLQITDIPLVAIAKGPDRNAGRERFFRPGQPPLTLE
PNDPVLHFLQRLRDEAHRTAIDSHRARRMKAISHSRIDGIPGIGPARKKALLHHFGSATA
VASAGLKDLEAAPGISEAIARKLYEHFHG