Protein Info for MPMX19_05787 in Azospirillum sp. SherDot2

Annotation: Methylglyoxal synthase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 155 TIGR00160: methylglyoxal synthase" amino acids 14 to 142 (129 residues), 163.1 bits, see alignment E=2e-52 PF02142: MGS" amino acids 42 to 121 (80 residues), 53.1 bits, see alignment E=1.5e-18

Best Hits

Swiss-Prot: 54% identical to MGSA_DESAG: Methylglyoxal synthase (mgsA) from Desulfovibrio alaskensis (strain G20)

KEGG orthology group: K01734, methylglyoxal synthase [EC: 4.2.3.3] (inferred from 90% identity to azl:AZL_d01460)

Predicted SEED Role

"Methylglyoxal synthase (EC 4.2.3.3)" in subsystem Methylglyoxal Metabolism (EC 4.2.3.3)

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 4.2.3.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (155 amino acids)

>MPMX19_05787 Methylglyoxal synthase (Azospirillum sp. SherDot2)
MTAQPSAPSPAKPRKRIALVAHDARKADLIAWIGANIGALDGHAFWATGTTGQKVRAAHP
GLDITPLKSGPLGGDQQIGAMIAEGRIDLLVFFVDPMTAQPHDVDVKALTRLATLYNIPM
ACNEATADMIVSSAHFASGYAPRAASFTDYETRKV