Protein Info for MPMX19_05554 in Azospirillum sp. SherDot2

Annotation: hypothetical protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 561 PF01584: CheW" amino acids 26 to 159 (134 residues), 79 bits, see alignment E=1.3e-26 amino acids 204 to 354 (151 residues), 90.5 bits, see alignment E=3.8e-30 amino acids 393 to 550 (158 residues), 107.7 bits, see alignment E=2e-35

Best Hits

KEGG orthology group: K03408, purine-binding chemotaxis protein CheW (inferred from 73% identity to azl:AZL_d03490)

Predicted SEED Role

"Positive regulator of CheA protein activity (CheW)" in subsystem Bacterial Chemotaxis or Two-component regulatory systems in Campylobacter

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (561 amino acids)

>MPMX19_05554 hypothetical protein (Azospirillum sp. SherDot2)
MTAVAGKVPREADGRAGGETDGVLDFVTVTVADLRLALPLSAVRAVIRLPELVRIPLGPP
SLDGLAHWHGDAVPVLDLAGALGRPGGAAPTRETRVVLVGHRGQPVGLRVDAMAGILRSE
PDRIDPVTQEEGGLDPAMLDGLLRDGPATILKLDALIDRQFGDPAETERTDRGSASATAG
FGPVPAGGTGAAGGAKGGIDRQALLVFEVAGQEFALPVDRVREVLPAPREVTRMARSKAH
LLGVMAVRDRLLPLVGLRALFGLEEAGGHEPSGLAAGRRVVVVRSGSGQAPVGVLVDEVR
EILRIDPALIDPVPPLLAREPEFEDLDGIARADGGAGGGRRLVSVLSAERLFRHGAAIGA
EGGAAEAGGQGDGMEPAQPADGPDGIGGAAERFVVFRLAGAEYGLPVSAVREVLRRPDSI
TPLPNAPDFVAGVLTLRGEVLPLIDQRRLLNLPAADSKSGLSTSGPAGLERGRVVVVGRD
GLLVGLLVDGLSGLLTVPAERIGPAPAVSAAQRRLIRRVASLDAAGDMAGDAAGAARLIL
LMDADSLLDMDRLAELPVTPR