Protein Info for MPMX19_05513 in Azospirillum sp. SherDot2

Annotation: 3'3'-cGAMP-specific phosphodiesterase 2

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 521 PF00072: Response_reg" amino acids 44 to 154 (111 residues), 30.5 bits, see alignment E=7.3e-11 PF11849: DUF3369" amino acids 165 to 317 (153 residues), 69.9 bits, see alignment E=6.2e-23 PF13487: HD_5" amino acids 329 to 506 (178 residues), 113 bits, see alignment E=2.7e-36 PF01966: HD" amino acids 340 to 474 (135 residues), 53.9 bits, see alignment E=4.2e-18

Best Hits

KEGG orthology group: None (inferred from 86% identity to azl:AZL_d00790)

Predicted SEED Role

"Response regulator"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (521 amino acids)

>MPMX19_05513 3'3'-cGAMP-specific phosphodiesterase 2 (Azospirillum sp. SherDot2)
MVNGGKGADRADTLRRDSAGDILEFAAEAEETADGGRRNPPWLILIVDDDHEVHAITRVV
LGEMMFEERPLRFLSAYTARQARSLLAEHPGIAAILLDVVMETDDAGLKLVRHIREEMGN
RQIRIILRTGQPGQAPERQVIAAYDINDYKAKSELTAQKLYTAAVAALRSYQHIATIEHG
RQGLERVMEAADHLAGLRSRPQFLAGLVGRAAALATGAHSALLCAAGKDGQPSIVAEAGL
PAELPAEAAATIMAALADGQTRWSERCGVAVLRGRDAPMLALCLLGGPFAAGDRPLVELL
CTKAAVGLDNLRLYERLNQAQIATVHALGKLAEYKDEVTGDHVKRLGRWATAIARELQAR
NTFAHELDDWFCDTIGLASVLHDVGKVGIPDAILRKPGRLDEAEMTVMREHAAIGGSILR
DACGGDRHGYLSMGAEIAESHHEKFDGSGYPKGLAGDAIPLAGRIVAVADVFDALLHRRP
YKKAWDIAEVLDLLRAEAGSHFDPRVVDAFLTVLERDGAGT