Protein Info for MPMX19_05207 in Azospirillum sp. SherDot2

Annotation: Hemolysin secretion protein D, plasmid

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 438 signal peptide" amino acids 1 to 11 (11 residues), see Phobius details transmembrane" amino acids 12 to 29 (18 residues), see Phobius details TIGR01843: type I secretion membrane fusion protein, HlyD family" amino acids 6 to 438 (433 residues), 387.1 bits, see alignment E=5.4e-120 PF00529: CusB_dom_1" amino acids 20 to 416 (397 residues), 33.3 bits, see alignment E=7.8e-12 PF13533: Biotin_lipoyl_2" amino acids 56 to 85 (30 residues), 30.3 bits, see alignment (E = 5.5e-11) PF13437: HlyD_3" amino acids 272 to 359 (88 residues), 58.6 bits, see alignment E=1.8e-19

Best Hits

KEGG orthology group: K11003, hemolysin D (inferred from 89% identity to azl:AZL_a02360)

Predicted SEED Role

"HlyD family secretion protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (438 amino acids)

>MPMX19_05207 Hemolysin secretion protein D, plasmid (Azospirillum sp. SherDot2)
MDTPPSPFARAVSLLIVAFAVIAVAWAWIGHIDITAVTRGRLIPSDRNKLVQTLEPGIVR
AIRVTEGQQVEQGAVLLELDPTDSAADAGRAEWELAVAETEASRLRAALADRRSFDPPPT
ADAALVALQRSILVNQLTARDAALDAIGSQERQRRAEIAALAAEKARLGATLPLIREQVQ
AKRNLSQRGYSPRFDLLELEKELAEVEYGAVAAKNREAEAEAALKGLADERRRVTAEFDG
KAMADLADAEKRAAALRQELTKAARRRERQLLTAPVGGMIQQLAVHTVGGVVTAAEPLMV
IVPANRTLIVEVQVENKDIGFLHPGMPAEIKVDAFPFTRYGLLPGTVLAVSHDVILPPDG
AAARTGAAEPAATAERDGPKFSARIALERTAIRGETGEDIALAPGMAVTAEVKTGRRRVL
DYLLSPVLAHVHEAMRER