Protein Info for MPMX19_05206 in Azospirillum sp. SherDot2

Annotation: Toxin RTX-I translocation ATP-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 720 transmembrane" amino acids 159 to 180 (22 residues), see Phobius details amino acids 193 to 213 (21 residues), see Phobius details amino acids 266 to 291 (26 residues), see Phobius details amino acids 297 to 317 (21 residues), see Phobius details amino acids 362 to 383 (22 residues), see Phobius details amino acids 394 to 419 (26 residues), see Phobius details PF03412: Peptidase_C39" amino acids 10 to 130 (121 residues), 61.6 bits, see alignment E=1.1e-20 TIGR01846: type I secretion system ATPase" amino acids 14 to 710 (697 residues), 1016.3 bits, see alignment E=0 PF00664: ABC_membrane" amino acids 159 to 424 (266 residues), 173.9 bits, see alignment E=8.7e-55 PF00005: ABC_tran" amino acids 489 to 638 (150 residues), 119.3 bits, see alignment E=3.1e-38

Best Hits

Swiss-Prot: 56% identical to CYAB_BORP1: Cyclolysin secretion/processing ATP-binding protein CyaB (cyaB) from Bordetella pertussis (strain ATCC 9797 / DSM 5571 / NCTC 10739 / 18323)

KEGG orthology group: K11004, ATP-binding cassette, subfamily B, bacterial HlyB/CyaB (inferred from 96% identity to azl:AZL_a02350)

Predicted SEED Role

"cyclolysin secretion ATP-binding protein" in subsystem cAMP signaling in bacteria

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (720 amino acids)

>MPMX19_05206 Toxin RTX-I translocation ATP-binding protein (Azospirillum sp. SherDot2)
MPRLVEDSVTPDTGLSCLIFMLRLMGHPADPEQIRHDHAVRGRAMETLDILRAAKRFGLK
ARSVTTSWDRLAATPLPAIAKRRDGRYFIIAKIDGDRVLIQDPLESKPLALPRAVVEPAW
AGELVLMARRAGLDLAQVRFGIGWFVPALLKYRRLFSEILLASFMLQVFGLISPLFFQVV
VDKVLAHRSLTTLDILVVGLVVVSLFETVLGGLRSYLFSHTTSRVDVTLGARLFDHLLAL
PLPYFQARRVGDNVARVRELDRIRDFLTGSALTLVIDLVFTVVFLAVMWWYSPALTGIVL
ASLPVYAAISLAVTPVLRRRLEAKFALGAENQAFLVESISGIETLKAMAVEPEMRRHWEE
RLAAYVGAAFRASSLGVVAGQGVQLVSKLTMAALLYVGAQEVIDGALTIGALVAVNMLAG
RVSSPVLRLAQLWNDFQQARVSVERLADILNTTPEPAAKPGRLPLPAIRGRIRFDRVGFR
YRPDASPTLQGIDLTVEAGETVGIVGSSGSGKSTLTKLVQRLYVPESGRVLIDDVDLSLV
DVAWLRRQIGVVLQENVLFNRSIRDNIALADPGMPMERIVEAARLAGADRFILGLPEGYD
TVIGERGSSLSGGQRQRVAIARALATDPRILIFDEATSALDVESEAAIQANMRRICDNRT
VLIVAHRLSTVRGCDRIVTVEEGRIAEQGTHDELIRLGGRYAALWRMQAGGQAEVDHGVA