Protein Info for MPMX19_05073 in Azospirillum sp. SherDot2

Annotation: L-cystine transport system permease protein YecS

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 226 transmembrane" amino acids 15 to 46 (32 residues), see Phobius details amino acids 56 to 78 (23 residues), see Phobius details amino acids 84 to 103 (20 residues), see Phobius details amino acids 187 to 208 (22 residues), see Phobius details TIGR01726: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family" amino acids 15 to 110 (96 residues), 103.4 bits, see alignment E=3.8e-34 PF00528: BPD_transp_1" amino acids 34 to 216 (183 residues), 89.2 bits, see alignment E=1.4e-29

Best Hits

Swiss-Prot: 54% identical to Y1079_HAEIN: Probable amino-acid ABC transporter permease protein HI_0179 (HI_1079) from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)

KEGG orthology group: K02029, polar amino acid transport system permease protein (inferred from 97% identity to azl:AZL_c01350)

MetaCyc: 54% identical to cystine ABC transporter membrane subunit (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-290 [EC: 7.4.2.12]; 7.4.2.12 [EC: 7.4.2.12]; 7.4.2.- [EC: 7.4.2.12]; 7.4.2.- [EC: 7.4.2.12]; 7.4.2.- [EC: 7.4.2.12]; 7.4.2.- [EC: 7.4.2.12]

Predicted SEED Role

"Cystine ABC transporter, permease protein"

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.4.2.12

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (226 amino acids)

>MPMX19_05073 L-cystine transport system permease protein YecS (Azospirillum sp. SherDot2)
MLHWLTLMADSLPSLLWAALVFTVPLTLASFALGLVVGLVAAVVRLFGPAPLAAIVRFYV
WIIRGTPLLVQLFLIFYGLPSAGIVLDAFPAALIGFTLNVGAYTSEIIRAVIGSVPKGQW
EAAYSIGMSWSQAMRRTILPQAARVAVPPLSNSFISLVKDTSLAAAITVPELFQAAQRIV
ATSYEPLILYVEAALIYLALSSVLSALQVRLERRLNQYGGFLEAKS