Protein Info for MPMX19_04989 in Azospirillum sp. SherDot2

Annotation: K(+)/H(+) antiporter NhaP2

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 859 transmembrane" amino acids 26 to 46 (21 residues), see Phobius details amino acids 54 to 74 (21 residues), see Phobius details amino acids 96 to 113 (18 residues), see Phobius details amino acids 125 to 144 (20 residues), see Phobius details amino acids 150 to 174 (25 residues), see Phobius details amino acids 191 to 208 (18 residues), see Phobius details amino acids 229 to 246 (18 residues), see Phobius details amino acids 253 to 270 (18 residues), see Phobius details amino acids 275 to 294 (20 residues), see Phobius details amino acids 313 to 333 (21 residues), see Phobius details amino acids 341 to 370 (30 residues), see Phobius details amino acids 382 to 401 (20 residues), see Phobius details amino acids 412 to 436 (25 residues), see Phobius details amino acids 766 to 781 (16 residues), see Phobius details PF00999: Na_H_Exchanger" amino acids 37 to 437 (401 residues), 180.6 bits, see alignment E=4.5e-57 PF00027: cNMP_binding" amino acids 752 to 831 (80 residues), 69.4 bits, see alignment E=2.1e-23

Best Hits

KEGG orthology group: K03316, monovalent cation:H+ antiporter, CPA1 family (inferred from 91% identity to azl:AZL_c05030)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (859 amino acids)

>MPMX19_04989 K(+)/H(+) antiporter NhaP2 (Azospirillum sp. SherDot2)
MALPPPQCGDTVQPTPQPFRGTMHDIVIQVLGVAGLLALVSFLPPLAARFQMPYTVLLAG
VGVALGAVIQTFAGPGKDPLHDFLNSLAELDISSDVLLHVFLPILLFETALAVDVRRLFE
DLGPILLMAVVAVFVCTFAVGYAVNLFTPLPLVACLLLGAIVASTDPAAVIGIFRDLGAP
RRLTTLVEGEALLNDAAAIALFTLLLEMLTRTSHGGAAAAAVDFLRDFSGGVVTGYVCGR
IVCMLVEPVRNQPMAEITLTVALAYLSYVLADHYVGASGVVATVTSALVIGSVGRTRISP
ATWGAMEHVWQQLGFWANSMIFLLTAILVPRLLADAGWAEVGLVVVVVLAAFAARAVVLF
GLLPVLSWAGLAQKVSNSYKSVMLWGGMRGAVSLTLALAVTENFRVPDRLQSFIAVMVTG
FVFVTLFVNGTTLRWLIRLLKLDELTPVERAMRNRALALSTDSIRDRVSAVAQTYEVDGA
VKDVMIARYEERLKKIDRDSQEEAKLTDEDRVTIGLVILVNREEELYYAHFSEGVVSRAV
MEMLAGRSGRLLDAVKSQGRNGYRAFEEPFIAFSPWMRTASWLQRRFGIHSPLARRLSMR
FEVLVAVRTVLRELLAFTRDRLARVLGQEVAFVLEGMLVGRLGIVEQALSALKLQYPDYA
VVLQSRYVGRAALRLEHAEYRAMHAESIISQEVLTDLERDLEQRRRVLERLPKLDVRFDV
AELVRRVPLFAELPAERVATIATLLRAQLALPGETILRKGDRGDAMFFIASGAVEVLVPM
LAEPVKLGTGDFFGEMALLSRQRRNADVRALGYCQLLVLDEKDFRRLVQKDADLQSHIQA
VAEARRQPTQSSPAVPAVS