Protein Info for MPMX19_04881 in Azospirillum sp. SherDot2

Annotation: Putrescine transport system permease protein PotH

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 314 transmembrane" amino acids 21 to 48 (28 residues), see Phobius details amino acids 96 to 120 (25 residues), see Phobius details amino acids 132 to 154 (23 residues), see Phobius details amino acids 182 to 203 (22 residues), see Phobius details amino acids 226 to 250 (25 residues), see Phobius details amino acids 281 to 302 (22 residues), see Phobius details PF00528: BPD_transp_1" amino acids 116 to 300 (185 residues), 57.5 bits, see alignment E=7.7e-20

Best Hits

Swiss-Prot: 59% identical to POTH_ECOLI: Putrescine transport system permease protein PotH (potH) from Escherichia coli (strain K12)

KEGG orthology group: K11075, putrescine transport system permease protein (inferred from 95% identity to azl:AZL_c00710)

MetaCyc: 59% identical to putrescine ABC transporter membrane subunit PotH (Escherichia coli K-12 substr. MG1655)
ABC-25-RXN [EC: 7.6.2.11, 7.6.2.16]

Predicted SEED Role

"Putrescine transport system permease protein PotH (TC 3.A.1.11.2)" in subsystem Polyamine Metabolism (TC 3.A.1.11.2)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.6.2.11 or 7.6.2.16

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (314 amino acids)

>MPMX19_04881 Putrescine transport system permease protein PotH (Azospirillum sp. SherDot2)
MRTVVSVLVSGLSRIGLWGRGVVVAIPYLWLLLFFMVPFLIVFGISFAESIIAQPPYSSL
VDWLTDEDAGTSKLQILLNISNYFRLGGDDLYILAYLNSLRIAAVTTLMCLAIGYPMAYA
IAKADPARRGPLMMLVILPFWTSFLIRIYAWIGILKGNGVISNLLEWVGITSGPVEILYS
DWAVYIGMTYCYLPFMVLPLYSTLEKMDPSLLEAAADLGSRPFKSFLSITLPLSLPGIIA
GSLLVFIPAVGEFVTPELLGGPDTLMIGRVLWNEFFANRDWPVASAVAIALLLVLVVPIM
IFQHVQGKQAEAGQ