Protein Info for MPMX19_04852 in Azospirillum sp. SherDot2

Annotation: Altronate oxidoreductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 501 PF01232: Mannitol_dh" amino acids 28 to 140 (113 residues), 49.9 bits, see alignment E=4.2e-17 PF08125: Mannitol_dh_C" amino acids 214 to 473 (260 residues), 181.5 bits, see alignment E=2e-57

Best Hits

Swiss-Prot: 44% identical to UXAB_YERPE: Altronate oxidoreductase (uxaB) from Yersinia pestis

KEGG orthology group: K00041, tagaturonate reductase [EC: 1.1.1.58] (inferred from 93% identity to azl:AZL_c04510)

Predicted SEED Role

"Altronate oxidoreductase (EC 1.1.1.58)" in subsystem D-Galacturonate and D-Glucuronate Utilization (EC 1.1.1.58)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.1.1.58

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (501 amino acids)

>MPMX19_04852 Altronate oxidoreductase (Azospirillum sp. SherDot2)
MHSLTRDQLAGGAFDVAHTDGAPTLPVTILQVGDGNFLRGFVDWMVDVANGQGLTKAGVA
IAQPLDQGIAPLLNAQDNLYTVLLRGIENGQEVESRRVVSCVSEALNPYADWARMVELAV
SPALRFFVSNTTEAGIADREEAYAPGTCPDSFPAKVAALLHARYTALGGSADSGLVFLPC
ELIEANGTNLKRIVLAHAKRWGLEAGFADWIETHNHFLNTLVDRIVPGYPKDEAAALSAK
WGYEDRLAVAAEPFHVWVIEGPAHLADELPLHKAGLNVVWTDDLQPYRTRKVRILNGAHT
ASALAAYCAGLDTVKSMMDDPTVSAYLNTVMFEEIVPYVPLPEAERQDYARTIMERFGNP
YIRHELISITLNSVSKWQVRVLPSLKDAVVRNGSAPAGLSFSLAALLRFYRGELSGGAYA
GTREAGSYPISDNAEVIAAMSAAWAANGSDPKALVAAILSDVRLWKEDLTAVPGLAARVA
DSLAAIEAKGMKAAMADLVAG