Protein Info for MPMX19_04726 in Azospirillum sp. SherDot2

Annotation: Glycine betaine/choline transport system permease protein OusW

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 294 transmembrane" amino acids 32 to 57 (26 residues), see Phobius details amino acids 64 to 85 (22 residues), see Phobius details amino acids 91 to 114 (24 residues), see Phobius details amino acids 135 to 161 (27 residues), see Phobius details amino acids 215 to 237 (23 residues), see Phobius details amino acids 245 to 263 (19 residues), see Phobius details PF00528: BPD_transp_1" amino acids 106 to 267 (162 residues), 105 bits, see alignment E=2e-34

Best Hits

Swiss-Prot: 47% identical to OPUAB_BACSU: Glycine betaine transport system permease protein OpuAB (opuAB) from Bacillus subtilis (strain 168)

KEGG orthology group: K02001, glycine betaine/proline transport system permease protein (inferred from 92% identity to azl:AZL_c01840)

Predicted SEED Role

"L-proline glycine betaine ABC transport system permease protein ProW (TC 3.A.1.12.1)" in subsystem Choline and Betaine Uptake and Betaine Biosynthesis (TC 3.A.1.12.1)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (294 amino acids)

>MPMX19_04726 Glycine betaine/choline transport system permease protein OusW (Azospirillum sp. SherDot2)
MDFEIRIGKWVEELVTFMLDHFQPTFDAIATVVNGFGGAIDFVLVGAPAWLLIGLIVATS
LWRVGIGFAVFTVAALSLIAGMGLWTETASTLGLVLTATLLSLLIGVPLGVWMARNRVVE
SIVRTTLDFMQTMPAFVYLIPAVMFFGLGRVPGILATVIFAMPPAVRLTSLGIQQVPAEI
VEAGKAFGCHDRQLLFKVQLPNALPSIMAGVNQTMMMALSMIVIASMIGAGGLGNVVLQG
IQRLDIALGFESGLSVVLLAIVLDRITQSFGQTAAAPRPVRFAFLRRFLPVPAR