Protein Info for MPMX19_04695 in Azospirillum sp. SherDot2

Annotation: Na(+)/H(+) antiporter subunit D

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 542 transmembrane" amino acids 6 to 26 (21 residues), see Phobius details amino acids 35 to 56 (22 residues), see Phobius details amino acids 76 to 102 (27 residues), see Phobius details amino acids 112 to 131 (20 residues), see Phobius details amino acids 135 to 154 (20 residues), see Phobius details amino acids 165 to 188 (24 residues), see Phobius details amino acids 214 to 236 (23 residues), see Phobius details amino acids 246 to 268 (23 residues), see Phobius details amino acids 279 to 302 (24 residues), see Phobius details amino acids 309 to 330 (22 residues), see Phobius details amino acids 336 to 354 (19 residues), see Phobius details amino acids 401 to 428 (28 residues), see Phobius details amino acids 443 to 465 (23 residues), see Phobius details amino acids 483 to 504 (22 residues), see Phobius details PF00361: Proton_antipo_M" amino acids 132 to 359 (228 residues), 76.9 bits, see alignment E=8.4e-26

Best Hits

KEGG orthology group: K05561, multicomponent K+:H+ antiporter subunit D (inferred from 92% identity to azl:AZL_c01220)

Predicted SEED Role

"Na(+) H(+) antiporter subunit D" in subsystem Sodium Hydrogen Antiporter

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (542 amino acids)

>MPMX19_04695 Na(+)/H(+) antiporter subunit D (Azospirillum sp. SherDot2)
MSGWMDHLTIAPIVVPLLAGAVMMLIDERQRTLKAAIGMASALMLLGLAILALSVADTGA
AGIRVYRLGNWPANFGIVLVLDRFAALMLVLTGILGVAALTFSLPRWQKAGAHFHPLFQF
QLMGLNGAFLTGDLFNLFVFFEIMLAASYGLALHGSGLARVRAGLHYVAINLSASLLFLI
GVSMIYGVSGTLNMADLAGRVASLAAEDRGLLEAGAAILGLAFLIKAGMWPLGFWLPNTY
STLGSASAAIVSILSKVGIYAVLRLWLLVFGEGAGASSGFGGTVLLIGGLLTIGFGCIAV
LATQNMARLAGATVLVSSGTLLAAIGAGQMAVTGGVLFYLTSSVMAVAGFFLLVELVERG
RGVGADVLAVTREAFGEGDDEDADDGGGGGGAGVPIPATMAILGIGFMSSALLLAGLPPL
SGFLAKFAILSPLLAAGPEVPVTTWILLAALVLSGLATVVAMTRVGIDAFWASPAAEVPR
VRVAEIAPVLLLLALNLALTIQAGPAMRYMEDTARALHAPQDYNGAVLSGIPMAGPTAGG
AR