Protein Info for MPMX19_04627 in Azospirillum sp. SherDot2

Annotation: HTH-type transcriptional regulator DegA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 337 signal peptide" amino acids 1 to 30 (30 residues), see Phobius details PF00356: LacI" amino acids 10 to 53 (44 residues), 55.2 bits, see alignment 7.1e-19 PF00532: Peripla_BP_1" amino acids 65 to 307 (243 residues), 85.1 bits, see alignment E=9.2e-28 PF13377: Peripla_BP_3" amino acids 172 to 329 (158 residues), 113.5 bits, see alignment E=1.8e-36

Best Hits

KEGG orthology group: K03435, LacI family transcriptional regulator, fructose operon transcriptional repressor (inferred from 94% identity to azl:AZL_c02640)

Predicted SEED Role

"Fructose repressor FruR, LacI family" in subsystem Fructose utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (337 amino acids)

>MPMX19_04627 HTH-type transcriptional regulator DegA (Azospirillum sp. SherDot2)
MSVSGKTAGIKDVALAAGVSVATVSRVLSNGPVSDTLRRRVEDAVRATGYRPNLSARRLR
SQHSQTIGLVVSDIRNPFFTAVSRAVEDAAYRAGMRVILCNSDENPEREELYLRLMQEER
ITGLIFAPTRATLDRLDGLDLDFPVVLIDRNAPTGRHDAVVLDNPRAAVMLVEHLHAQGY
RRIAGLFGNTSTTGQERHEGYRAAMTARGLAPAARFLAPHADAAEEAVVAWMAERDRPEA
FIVSNSLFLMGVVKAARRLRLPIPDGLAVAGFDNEPWTELVGPGLTVIEQPVQDIGQSAM
ALLFERLEAPDRPSRRLILGGTCIVRGSTAARMAAAD