Protein Info for MPMX19_04593 in Azospirillum sp. SherDot2

Annotation: Adaptive-response sensory-kinase SasA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 832 signal peptide" amino acids 1 to 34 (34 residues), see Phobius details transmembrane" amino acids 162 to 182 (21 residues), see Phobius details amino acids 473 to 492 (20 residues), see Phobius details PF08521: 2CSK_N" amino acids 19 to 158 (140 residues), 129.9 bits, see alignment E=2.2e-41 PF00512: HisKA" amino acids 237 to 293 (57 residues), 39.3 bits, see alignment 1.7e-13 PF02518: HATPase_c" amino acids 346 to 456 (111 residues), 78.5 bits, see alignment E=1.6e-25 PF13531: SBP_bac_11" amino acids 519 to 770 (252 residues), 51.4 bits, see alignment E=3.9e-17 PF01547: SBP_bac_1" amino acids 525 to 767 (243 residues), 38.2 bits, see alignment E=5.4e-13 PF13343: SBP_bac_6" amino acids 563 to 775 (213 residues), 47.3 bits, see alignment E=6e-16

Best Hits

Predicted SEED Role

"Sensor protein PhoQ (EC 2.7.13.3)" in subsystem Lipid A modifications (EC 2.7.13.3)

Isozymes

Compare fitness of predicted isozymes for: 2.7.13.3

Use Curated BLAST to search for 2.7.13.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (832 amino acids)

>MPMX19_04593 Adaptive-response sensory-kinase SasA (Azospirillum sp. SherDot2)
MAGGSLRRRLLTRMFVVLGVVTLILFLFVRTYAREAADSAYDQLLSASALSIADAVRVEN
GAITVDLPYSSLSVLGTARHDRVFYKVMAPGGLIVTGYEDLPGATVHDDTPVFQNAVYSD
APVRIAVTGRFISGVARSGWVTVVVAQTREARDLLASRLVANSFAPIAFAVVVGALLLWF
GVRQALVPLGFLESLIRARPPQDFSPIDAPVPTEVGQLLAAINQLMIRFKANLDSTQSFL
ADAAHQIRTPLAALRSQAELARREADVERLRNRVERIHRNAVEASELTTQLLNHATVVHR
AEAVQPQVVDLDALLRQIVQQMAGRPDAPPIALAREPAEGDALLHGDPVTLREALTNLLD
NAVKYGGANPVEVLVRPGTGDYGPLVEIADRGPGIPDGEKSKVFERFSRGRLSKGIAGSG
LGLSIAAAVAEAHHAALSLHDRPGGGLVVRLEFPAPAQPGEGAANGIPAGRRLLPLILLL
AVALPLVAAGPARALEPVLYPAPAGPTPAGGTERLRIDAATDRPAIEPLIRDFQRENPTV
TIEFREMNTGELYDSVVKRAAGDVPDLVISSASGLQVKLVNDGHARRYSSPATQALPDWA
NWRSAAFGFTQEPAAIVYNRDLVPAEDVPRSREDLIHLLRDRKERYRGRVVTYNVEESGI
GYLFATQDSVLTSQFWQLADALGENQARQMCCTSDMVDAIERGETYIGYNLLGSYARERQ
IHGAHIGIVLPSDYTLVMTRVALIPQRASAPELAGRFIDYLLSERGQSVVAGSTAFYSIQ
PTVGGPMSATHLQEEMRGPTQRIGLGPALLVYMDHLKRARFLQQWKAFLHQP