Protein Info for MPMX19_04508 in Azospirillum sp. SherDot2

Annotation: Phosphoglycolate phosphatase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 230 PF00702: Hydrolase" amino acids 13 to 193 (181 residues), 118.4 bits, see alignment E=1.3e-37 PF12710: HAD" amino acids 16 to 190 (175 residues), 48.3 bits, see alignment E=4.3e-16 TIGR01449: phosphoglycolate phosphatase, bacterial" amino acids 16 to 226 (211 residues), 220 bits, see alignment E=5.4e-69 PF13419: HAD_2" amino acids 16 to 198 (183 residues), 124.3 bits, see alignment E=1.6e-39 TIGR01509: HAD hydrolase, family IA, variant 3" amino acids 98 to 199 (102 residues), 38.8 bits, see alignment E=2.1e-13 TIGR01549: HAD hydrolase, family IA, variant 1" amino acids 101 to 193 (93 residues), 39.1 bits, see alignment E=2e-13 PF13242: Hydrolase_like" amino acids 155 to 199 (45 residues), 39.5 bits, see alignment 1e-13

Best Hits

Swiss-Prot: 48% identical to GPH_RHORT: Phosphoglycolate phosphatase (cbbZ) from Rhodospirillum rubrum (strain ATCC 11170 / ATH 1.1.1 / DSM 467 / LMG 4362 / NCIB 8255 / S1)

KEGG orthology group: K01091, phosphoglycolate phosphatase [EC: 3.1.3.18] (inferred from 55% identity to rce:RC1_4069)

Predicted SEED Role

"Phosphoglycolate phosphatase (EC 3.1.3.18)" in subsystem 2-phosphoglycolate salvage or Glycolate, glyoxylate interconversions or Photorespiration (oxidative C2 cycle) (EC 3.1.3.18)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.1.3.18

Use Curated BLAST to search for 3.1.3.18

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (230 amino acids)

>MPMX19_04508 Phosphoglycolate phosphatase (Azospirillum sp. SherDot2)
MTDTADSLNRPAIRAVAFDLDGTLVDSVADLMHASNALLAELGRPPVDLAAVRSFVGDGA
PKLVERVLAATGGVPAADEAARCLERFLAIYGADPSAHSTLYPGVAETLGRLAEAGLRLG
VCTNKPMAATLRLLDDLGIAGRFAAVVGGDSYPSRKPSPEPVLGLLERLGVAPAQTVFVG
DNEHDVAAARAAGVAQVLVVPYGYARVPLDGLPHDGILDGFADLAERLSC