Protein Info for MPMX19_04491 in Azospirillum sp. SherDot2

Annotation: Sensor histidine kinase RcsC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 838 PF08448: PAS_4" amino acids 49 to 143 (95 residues), 25 bits, see alignment E=6.4e-09 amino acids 185 to 301 (117 residues), 27.7 bits, see alignment E=9.4e-10 PF00989: PAS" amino acids 178 to 296 (119 residues), 25.3 bits, see alignment E=4.5e-09 amino acids 319 to 427 (109 residues), 24.3 bits, see alignment E=9.7e-09 TIGR00229: PAS domain S-box protein" amino acids 246 to 303 (58 residues), 23.8 bits, see alignment 2e-09 amino acids 361 to 434 (74 residues), 30.4 bits, see alignment E=1.8e-11 PF08447: PAS_3" amino acids 336 to 423 (88 residues), 55.8 bits, see alignment E=1.6e-18 PF02518: HATPase_c" amino acids 585 to 700 (116 residues), 63.2 bits, see alignment E=1e-20 PF00072: Response_reg" amino acids 722 to 824 (103 residues), 50.8 bits, see alignment E=5.9e-17

Best Hits

Predicted SEED Role

"FOG: PAS/PAC domain"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (838 amino acids)

>MPMX19_04491 Sensor histidine kinase RcsC (Azospirillum sp. SherDot2)
MSATLPDLEACDWSATPLGPREGWSPALDAIFTMMLASPFAMCATWGPEQTLLYNAAYVP
FLGKRHPAALGQPIAAVWSEVWDTIGPLIARVLEGEAVSFTDMHLVMTRNGCEEDTWWTF
AYSPLRDGGRVVGMLDIATETTAGVIAARQRDAVEAELRARNVALEQEVAARTEAGNRFS
TLIQHLPVGVCLLDGDGRALLSSPLYRELLPDEPVPSRMTNREEADRWRSFDADGERLPP
SRYPAARALRGEVVSPGIEFLHRKMDGTECWFAVSSVPLTDGAGQVSGAIAMLEDIDHRK
RALETARTDAERVQLALSAGAIIGTWFWDLPTDRFTVDEAFAATFGLDPALGRDGISLAQ
VVETVHPDDRAGLAEAMGEAIARGGRYAHQYRVRRHDGRYYWIEANGRVDLDADGTPRGF
PGVLIDVEERRTIVAERDRAIAELRSLNDTLEQRVAERTAELMQAEEKLRQAQKMEAVGQ
LTGGMAHDFNNLLQAMSGCLQLVGRRAGHVAGVQKVLESGHQAVDRGASMIRQLMAFSRR
QSLEPEAFDIRDRLLGMRSFLDRALRADIRLEFDLEGGLWPAMADPVQFELAILNLATNA
RDAIAGAGRLMIGAGNVEQCGEHGLHGSFVRIWVRDSGHGMAPAMLERIFEPFFTTKPVG
QGTGLGLAQVYGFCRQSGGIATVDSVEGQGTKVTLLLPRAETMPVAAVDVQRAMVDGGGA
SVLLVEDDPVVALVIVAALEEIGYQVSRATTGEEALRLLRDGERPDLLFTDVVMPGEIDG
AALAAAARVLLPRLAVVLTTGYSEDRAALKGFPVLSKPYRIEDLALTLRQEIDRSARL