Protein Info for MPMX19_04489 in Azospirillum sp. SherDot2
Annotation: D-threonine aldolase
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: None (inferred from 69% identity to axy:AXYL_04873)Predicted SEED Role
"D-serine deaminase (EC 4.3.1.18)" (EC 4.3.1.18)
MetaCyc Pathways
- superpathway of L-lysine, L-threonine and L-methionine biosynthesis II (12/15 steps found)
- glycine betaine degradation III (6/7 steps found)
- D-serine degradation (3/3 steps found)
- L-cysteine degradation II (3/3 steps found)
- L-serine degradation (3/3 steps found)
- glycine betaine degradation I (6/8 steps found)
- L-tryptophan degradation II (via pyruvate) (2/3 steps found)
- purine nucleobases degradation II (anaerobic) (17/24 steps found)
- L-methionine biosynthesis II (4/6 steps found)
- felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis (2/5 steps found)
- L-mimosine degradation (4/8 steps found)
- glutathione-mediated detoxification I (3/8 steps found)
KEGG Metabolic Maps
Isozymes
No predicted isozymesUse Curated BLAST to search for 4.3.1.18
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (428 amino acids)
>MPMX19_04489 D-threonine aldolase (Azospirillum sp. SherDot2) MSMFLDALLDSSLDDSIRGVPPGTAPLRLRDVGAQGWRPAAGDMALPVLTLDEDAFAANR DLILAYARHHGVALAPHAKTPMAPQIAAALVEAGAWGATVANLQQAAVLLRAGVTRLILG NEIGGIASGRRLGALLAAHPDADLRAFADSPAAVETLAAAARTSGRPLAVLVEVGAGRGG ARDRAAVEAILAAVRGHPGLLVLDGVATYEGAVATSDPAQTAANIAALMERTAEAFALVR ALAPDRPLMLTAGGSAFFDMVVAALTPVAKADGNATLVLRSGAIFFHDHGTYERALGALD ARKGFACGGATAADFRPALRLWAEVLTRPEPDLAICGFGMRDSSFDQDLPRPLRIHRDGM ALPAEGLRVTRLNDQHAFVAVPAGQELAVGDIVEFGISHPCTCIDRWRVLFGLGADGRVR CAYRTFFG