Protein Info for MPMX19_04439 in Azospirillum sp. SherDot2

Annotation: Pca regulon regulatory protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 277 TIGR02431: beta-ketoadipate pathway transcriptional regulators, PcaR/PcaU/PobR family" amino acids 25 to 269 (245 residues), 344 bits, see alignment E=2.1e-107 PF09339: HTH_IclR" amino acids 30 to 80 (51 residues), 55.2 bits, see alignment 5e-19 PF01614: IclR" amino acids 144 to 266 (123 residues), 118 bits, see alignment E=2.6e-38

Best Hits

Swiss-Prot: 55% identical to PCAR_PSEPU: Pca regulon regulatory protein (pcaR) from Pseudomonas putida

KEGG orthology group: K02624, IclR family transcriptional regulator, pca regulon regulatory protein (inferred from 95% identity to azl:AZL_a03500)

Predicted SEED Role

"Pca regulon regulatory protein PcaR" in subsystem Protocatechuate branch of beta-ketoadipate pathway

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (277 amino acids)

>MPMX19_04439 Pca regulon regulatory protein (Azospirillum sp. SherDot2)
MAETQQLAGAADKTPSGAAEEASDPNFMTSLARGLSVIRAFTEREPNLTIADIAKITGLP
RAAARRCLLTLMQLGYAGSDGRTFHLKPKILALGYSFLSSAPLATILDPLIEQVSGAVQE
SCSAAVLDEDDVVYIARAATKRIMSVGLNVGSRLPAYCTSMGRVLLAALPEAELNAYLAR
VPLKPFTERTITAPDALKRELERVRDRGFSLVDQELELGLRSIAVPISTAAGGVVAAMNI
SAQAARVTCPEMEVQFLPHLHRASEEARVLLVRSRGV