Protein Info for MPMX19_04315 in Azospirillum sp. SherDot2

Annotation: Nuclease SbcCD subunit D

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 414 PF00149: Metallophos" amino acids 4 to 237 (234 residues), 47.1 bits, see alignment E=4.1e-16 TIGR00619: exonuclease SbcCD, D subunit" amino acids 5 to 261 (257 residues), 181.2 bits, see alignment E=1.6e-57 PF12320: SbcD_C" amino acids 297 to 389 (93 residues), 42.6 bits, see alignment E=6.6e-15

Best Hits

KEGG orthology group: K03547, exonuclease SbcD (inferred from 87% identity to azl:AZL_a04600)

Predicted SEED Role

"Exonuclease SbcD" in subsystem DNA repair, bacterial

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (414 amino acids)

>MPMX19_04315 Nuclease SbcCD subunit D (Azospirillum sp. SherDot2)
MRSFRLLHTADWHLGQTLHGIPRDAEHACFLDWLIDRIGEHRVDALVIAGDVFDGQNPPI
PALALFYRFVARAKAQHPRLDIVVVAGNHDSASRLEAPSPLMTEMGVRVIGTLPASAAGM
FDPSPLIVPLHDADGTVAARCVAMPYLRPSDLPAVEEAEDIDPLIEGVRRLYSQAWSGGR
ERCGRSEALILTGHCYMRGGALSELSERKILGGNLHALPVDIFPDDAAYVALGHLHRAQA
VGGREAVRYSGSPIPLALDEQPYPHQVVLTEFAGGRLVGHEALRVPRHVAIHRVSEASPE
AALDRLKRLELDNGLPRDAWPFLEVTVTLPEPRPALRDEVEALLAGRPVRLLKLGVRLTG
SGQTLADSAPPVDLASLEPEEVFRRLYRRSHDGDPEPDLMAAFHELLTGVQETM