Protein Info for MPMX19_04287 in Azospirillum sp. SherDot2

Annotation: Colistin resistance protein EmrB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 517 transmembrane" amino acids 16 to 36 (21 residues), see Phobius details amino acids 56 to 76 (21 residues), see Phobius details amino acids 83 to 104 (22 residues), see Phobius details amino acids 110 to 134 (25 residues), see Phobius details amino acids 142 to 164 (23 residues), see Phobius details amino acids 170 to 192 (23 residues), see Phobius details amino acids 204 to 224 (21 residues), see Phobius details amino acids 237 to 257 (21 residues), see Phobius details amino acids 275 to 295 (21 residues), see Phobius details amino acids 310 to 331 (22 residues), see Phobius details amino acids 339 to 356 (18 residues), see Phobius details amino acids 374 to 393 (20 residues), see Phobius details amino acids 406 to 424 (19 residues), see Phobius details amino acids 481 to 505 (25 residues), see Phobius details TIGR00711: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family" amino acids 19 to 502 (484 residues), 462.6 bits, see alignment E=7.9e-143 PF07690: MFS_1" amino acids 23 to 416 (394 residues), 154.7 bits, see alignment E=1.5e-49

Best Hits

Swiss-Prot: 46% identical to EMRB_ACIBT: Colistin resistance protein EmrB (emrB) from Acinetobacter baumannii (strain ATCC 17978 / CIP 53.77 / LMG 1025 / NCDC KC755 / 5377)

KEGG orthology group: None (inferred from 97% identity to azl:AZL_a05390)

Predicted SEED Role

"Multidrug resistance protein B"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (517 amino acids)

>MPMX19_04287 Colistin resistance protein EmrB (Azospirillum sp. SherDot2)
MATPAQGMRPLTPRDIAGFFAMVVGMFMAILDIQIVSSSLSEIQAGLAASADEISWVQTS
YLIAEVVMIPLSGILSRIMSTRVLFTLAAAGFTLTSVACAFAGGIESMIVWRALQGFIGG
AMIPTVFATSFMIFPPEKRAGVSVMMGLVATMAPTIGPTLGGYLTQHLSWHWLFLANVIP
GILVTSLVWFLVDVDRPNPELRKGFDFLGLGLMAAFLGSLEYVVEEGPRNDWFDDEAIFA
LAVVAAVSAAGFFWRVLSYRNPIVELRAFADRNFAIGSLYSFILGIGLYGSVYLQPLFLA
RVRGFNSLQIGEIMFVTGIFQFMSAPIAGALSKRMDLRAMLALGLILFGTGVWLNSHFTA
DTGFWELFLPQAVRGMSLMLCFIPINSVALGTLSPDKLKNASGLYNLMRNLGGAIGLAAI
NTVLTDRNALHLNRLGDNVNLARPEVQQMVDSLSQRFDGLVADPTAAAMSRLVGLVQREA
LILTFNDAMLLMSAVFFGALLFMPLVRRPGAPVKADH