Protein Info for MPMX19_04218 in Azospirillum sp. SherDot2

Annotation: Protein phosphatase PrpC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 271 signal peptide" amino acids 1 to 20 (20 residues), see Phobius details PF13672: PP2C_2" amino acids 19 to 226 (208 residues), 45.4 bits, see alignment E=7.6e-16

Best Hits

KEGG orthology group: K01090, protein phosphatase [EC: 3.1.3.16] (inferred from 78% identity to azl:AZL_a06430)

Predicted SEED Role

"Protein serine/threonine phosphatase PrpC, regulation of stationary phase" in subsystem Conserved gene cluster associated with Met-tRNA formyltransferase

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.1.3.16

Use Curated BLAST to search for 3.1.3.16

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (271 amino acids)

>MPMX19_04218 Protein phosphatase PrpC (Azospirillum sp. SherDot2)
MPNAAFALTVAGLTDVGRARSRNEDDFQVSIAGEFAVVCDGMGGHAGGDIASRKAVEVIS
GILLGHAPSNPITLAKRDDADRTQTDPAATEPAVRHALSVARSAVQQANRTIYELNLARG
FSSGRGMGTTVAGLWRIPGTAYMAVFHAGDSRVYRLRDGELRTLTRDHSLYQIWLDNGGR
GTAPQRNIIVRALGTAEDVEPDVSVQSLMPDDVVMLCSDGLNGMLPDGVIARILRQESDP
ALAAAALVDAANAAGGMDNVTVVVGRFAATA