Protein Info for MPMX19_04130 in Azospirillum sp. SherDot2

Annotation: Aldehyde oxidoreductase molybdenum-binding subunit PaoC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF01315: Ald_Xan_dh_C
  • amino acids 36 to 148 (113 residues), 79.2 bits, E=4.4e-26
• PF02738: MoCoBD_1
  • amino acids 179 to 402 (224 residues), 174.6 bits, E=3e-55
• PF20256: MoCoBD_2
  • amino acids 425 to 700 (276 residues), 185.2 bits, E=2.9e-58

Best Hits

KEGG orthology group: K11177, xanthine dehydrogenase YagR molybdenum-binding subunit [EC: 1.17.1.4] (inferred from 61% identity to mno:Mnod_2924)

Predicted SEED Role

"Periplasmic aromatic aldehyde oxidoreductase, molybdenum binding subunit YagR"

MetaCyc Pathways

• purine nucleotides degradation II (aerobic) (11/11 steps found)
• adenosine nucleotides degradation II (5/5 steps found)
• guanosine nucleotides degradation III (4/4 steps found)
• inosine 5'-phosphate degradation (4/4 steps found)
• ureide biosynthesis (6/7 steps found)
• guanosine nucleotides degradation II (3/4 steps found)
• purine nucleobases degradation II (anaerobic) (17/24 steps found)
• adenosine nucleotides degradation I (5/8 steps found)
• guanosine nucleotides degradation I (2/4 steps found)
• superpathway of guanosine nucleotides degradation (plants) (3/6 steps found)
• purine nucleotides degradation I (plants) (7/12 steps found)
• superpathway of purines degradation in plants (9/18 steps found)
• caffeine degradation III (bacteria, via demethylation) (1/7 steps found)
• theophylline degradation (1/9 steps found)
• caffeine degradation IV (bacteria, via demethylation and oxidation) (1/10 steps found)

KEGG Metabolic Maps

• Purine metabolism

Isozymes

Compare fitness of predicted isozymes for: 1.17.1.4

Use Curated BLAST to search for 1.17.1.4

Protein Sequence (760 amino acids)

>MPMX19_04130 Aldehyde oxidoreductase molybdenum-binding subunit PaoC (Azospirillum sp. SherDot2)
MIAKPTIPDPLERPDTRPGSQIGKPVSRVDGRLKVTGGAKYAAEFNTPGLAHGSIVSSAI
ARGRILAIDTAKALALPGVFQVFTHENRPSLPWFDRKWKDDDAPKGSPFRPLYDATIHHA
LQPIALVVAESFELARYAARLIHVTYEADEHQTDLRAAKADAFTPGKDKGGFQPPPKPRG
DADTALAEAEVSVDLNFSQAVEHHNPMEMHASTVIYHNDGSLTVHDKTQGPINTQTYVCN
VFNLATDAVRVISPFVGGAFGSGLRPQHQLFMAVLAATALKRSVRVELTRPQMFSFGHRP
ETLQRVALGAKRDGTLTAVIHEAVQETSQTENYVEVVVNWSGQQYKCDNVRLDYKLARMD
THTPLDQRAPGAAIGVPALEIAMDELAAKLGMDPLELRLKNYTEVDPNTGKPFSSKELRA
CFQQGAERFGWHRRSHAPRSMREGRQLVGWGMATGVWDAMQGQAVASARLGIDGTLTVGS
ATADIGPGTYTAMTQIAADILGLPIEKVSFQLGDTNLPMAPLQGGSWTVSSVGSAVKAVC
DRLRDRLAGLAAGLNDGPLKGLKADELIFADGFLIAKADPSWRLSITEVMRANDLPVLED
EARSIPYYKSQMQHALGTHSAIFAEVRVDEDLGTVQVTRVVSAVAAGRIINPKTARSQVL
GAVVWGIGMALEEESMIDQRLGRFMNHDFGEYHIPVNADVHDIDVIFVEEHDDIVNPLGA
KGVGEIGIVGVPAAIANAIYHATGKRLCDLPITLDKILEA