Protein Info for MPMX19_04056 in Azospirillum sp. SherDot2

Annotation: Aldehyde oxidoreductase molybdenum-binding subunit PaoC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF01315: Ald_Xan_dh_C
  • amino acids 45 to 159 (115 residues), 80.7 bits, E=1.5e-26
• PF02738: MoCoBD_1
  • amino acids 183 to 406 (224 residues), 178.8 bits, E=1.6e-56
• PF20256: MoCoBD_2
  • amino acids 431 to 705 (275 residues), 196.4 bits, E=1.2e-61

Best Hits

KEGG orthology group: K11177, xanthine dehydrogenase YagR molybdenum-binding subunit [EC: 1.17.1.4] (inferred from 84% identity to atu:Atu5500)

Predicted SEED Role

"Xanthine dehydrogenase, molybdenum binding subunit (EC 1.17.1.4)" in subsystem Purine Utilization (EC 1.17.1.4)

MetaCyc Pathways

• purine nucleotides degradation II (aerobic) (11/11 steps found)
• adenosine nucleotides degradation II (5/5 steps found)
• guanosine nucleotides degradation III (4/4 steps found)
• inosine 5'-phosphate degradation (4/4 steps found)
• ureide biosynthesis (6/7 steps found)
• guanosine nucleotides degradation II (3/4 steps found)
• purine nucleobases degradation II (anaerobic) (17/24 steps found)
• adenosine nucleotides degradation I (5/8 steps found)
• guanosine nucleotides degradation I (2/4 steps found)
• superpathway of guanosine nucleotides degradation (plants) (3/6 steps found)
• purine nucleotides degradation I (plants) (7/12 steps found)
• superpathway of purines degradation in plants (9/18 steps found)
• caffeine degradation III (bacteria, via demethylation) (1/7 steps found)
• theophylline degradation (1/9 steps found)
• caffeine degradation IV (bacteria, via demethylation and oxidation) (1/10 steps found)

KEGG Metabolic Maps

• Purine metabolism

Isozymes

Compare fitness of predicted isozymes for: 1.17.1.4

Use Curated BLAST to search for 1.17.1.4

Protein Sequence (761 amino acids)

>MPMX19_04056 Aldehyde oxidoreductase molybdenum-binding subunit PaoC (Azospirillum sp. SherDot2)
MSAHSDAAASRPGRWQPAVTQDPLLQKHGALGQPVSRIEGPLKAQGKARFAAEFPYEGLC
YASLAFSTIARGRITALDTAAAEAAPGVVLVMTHRNAPRMKAPSLMMSSPSAAGASDLPV
MQTDEIHWNGQPIAVVLAETQEQADHAASLVTAGYAPLPAVTSFDEARKTPRQLDNILGQ
PPVVEIGDAEAALKGAAVQVDQIYRTPRHNHNAIELHAATVAWSGDELRVHDASQLLDLT
AGQLADIFGLAADKVRVSSPYVGGGFGGKCLWDHQILACAAAKLAGRPVRIMLSREGVFR
IVGGRTLTEQRVALGAGADGRLDALIHTGIAAMTAHNSCPEQFTFSARHLYAAKSIRLAQ
EVADMDMLANTFMRAPGESVGTFALECAIDELAEKLGLDPIELRRRIEPDKDPTSGKPFS
ARHLIDAYDKGAERFGWERRSPTPRQQRDGEWLIGMGCATATYPYHRFPGGAARIRLTAG
GQVTVSTAVHDMGMGTATAQVQHIAARLGLPLAQVSFEYGDTTLPRGVIAGGSTQTASIG
GAVIAATEVFVEELLKLAGNDSPLAGLSLADVETRDGGIGHRDDAARFESYESILRRSGR
GELVCEAEAPPPAEMEAFSMHSYGAQFCEVRVSEVTGEVRVSRFLGSFDAGRILNAKTAT
SQFKGGIIMGIGLALTEETNFDPRTGRIVNASLADYHVPVQMDVPAIEILYTDIPDPQAP
MGARGIGEIGITGVGAAVANAVYNATGKRIRDLPITLDKLM