Protein Info for MPMX19_03975 in Azospirillum sp. SherDot2

Annotation: Putative thiosulfate sulfurtransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00581: Rhodanese
  • amino acids 12 to 125 (114 residues), 38.4 bits, E=7.2e-14
  • amino acids 153 to 270 (118 residues), 41.9 bits, E=5.7e-15

Best Hits

KEGG orthology group: K01011, thiosulfate/3-mercaptopyruvate sulfurtransferase [EC: 2.8.1.1 2.8.1.2] (inferred from 86% identity to azl:AZL_a02730)

Predicted SEED Role

"Thiosulfate sulfurtransferase, rhodanese (EC 2.8.1.1)" (EC 2.8.1.1)

MetaCyc Pathways

• thiosulfate disproportionation IV (rhodanese) (1/1 steps found)
• L-cysteine degradation III (1/2 steps found)
• sulfide oxidation IV (mitochondria) (2/5 steps found)

KEGG Metabolic Maps

• Cysteine metabolism

Isozymes

Compare fitness of predicted isozymes for: 2.8.1.1, 2.8.1.2

Use Curated BLAST to search for 2.8.1.1 or 2.8.1.2

Protein Sequence (280 amino acids)

>MPMX19_03975 Putative thiosulfate sulfurtransferase (Azospirillum sp. SherDot2)
MTDSSISPLVDASWLKGRLDSPGIVVLDVRTPPAGGFVPGAVHSDYATAGWRTVVGGGAG
MLPDPGVLAGLIGGLGIGNGDHVVLVAAGANASDMGNATRVYWTFKMLGHDAVSVLDGGF
AAWIADGGPVTPEPAVRKPTGFVPHPRAGLRATVEDVEAAVKAGGTPLHDARSAEQFAGK
AKSPQARAPGTIPGAVNLDIAPLFSAAEHRFATPDAVKAMADRAALPLRDQPITFCNTGH
LASVSWFALSEIAGVPGVRLYDGSMSEWSADPERPLQTEG