Protein Info for MPMX19_03870 in Azospirillum sp. SherDot2

Annotation: L-aspartate dehydrogenase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 285 PF03447: NAD_binding_3" amino acids 27 to 136 (110 residues), 57.4 bits, see alignment E=2.4e-19 PF01958: Asp_DH_C" amino acids 185 to 271 (87 residues), 99.5 bits, see alignment E=1e-32

Best Hits

Swiss-Prot: 62% identical to ASPD_BRADU: Probable L-aspartate dehydrogenase (nadX) from Bradyrhizobium diazoefficiens (strain JCM 10833 / IAM 13628 / NBRC 14792 / USDA 110)

KEGG orthology group: K06989, aspartate dehydrogenase [EC: 1.4.1.21] (inferred from 62% identity to rpb:RPB_0147)

Predicted SEED Role

"L-Aspartate dehydrogenase (EC 1.4.1.21)" in subsystem NAD and NADP cofactor biosynthesis global (EC 1.4.1.21)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.4.1.21

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (285 amino acids)

>MPMX19_03870 L-aspartate dehydrogenase (Azospirillum sp. SherDot2)
MTETPLGLSQTPAHARALPPLRVAVAGLGAVGLKIVEALDEGLDGCVLTAVSARDKAAAA
DRLSALTHPVPVVDIAELEPLADLVVECAPAALLPAIVEPFLRAGKTAVVLSSGALLANE
GLVATARAHGGQIVVPTGALLGLDAVTAAAEGEIRAVRMVTRKPVRGLVGAPYLVENGIA
IEDITGPLRIFHGTPREAAVGFPANLNVAVALSLAGIGPDRTTLEIWADPALERNTHRIE
VEADSATFTMAIENIPTDNPKTGRITALSVLAYLRKLRAPLRVGS