Protein Info for MPMX19_03856 in Azospirillum sp. SherDot2

Annotation: Multidrug resistance protein MdtA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 373 signal peptide" amino acids 1 to 35 (35 residues), see Phobius details TIGR01730: efflux transporter, RND family, MFP subunit" amino acids 57 to 365 (309 residues), 175.9 bits, see alignment E=5.2e-56 PF16576: HlyD_D23" amino acids 70 to 269 (200 residues), 48.8 bits, see alignment E=8.3e-17 PF13533: Biotin_lipoyl_2" amino acids 74 to 110 (37 residues), 24.1 bits, see alignment 3.7e-09 PF13437: HlyD_3" amino acids 180 to 272 (93 residues), 34.2 bits, see alignment E=5.3e-12

Best Hits

KEGG orthology group: None (inferred from 75% identity to mno:Mnod_8533)

Predicted SEED Role

"Cell Processes; Protection responses; drug/analog sensitivity and resistance"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (373 amino acids)

>MPMX19_03856 Multidrug resistance protein MdtA (Azospirillum sp. SherDot2)
MKKRPMVVVGGVLTVVLGAAAVVTLSMHTQEASAVSDPRQEAPIVRLAAAVPVAGSDRGF
TGVVGARVQSNLGFRVPGKIIERLATVGQPVKAGQPLMRIDETDLRLALTAKRNAAAAAR
AVVVQTQADERRYASLLNDGWASRQRHEQAKAALDTARAQFASTEADARVAENEATYSVL
VADSDGTVVETLGEPGQVVAAGQTVVRLAQAGPREAVVALPETIRPQIGSPAEASLYGAD
GQRYGAHLRQLSDAADAQTRTYEARYVLDGDAAAAPLGATVTIRLTGRPGGQTDRADMQV
PLGAVLDDGRRTGVWTLERTSSTVRFQTVRLVRVSGDTAVISGLGLGDPVVSLGAHLLQE
GVRVRTAADSGVR