Protein Info for MPMX19_03745 in Azospirillum sp. SherDot2

Annotation: Potassium-transporting ATPase potassium-binding subunit

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 569 transmembrane" amino acids 6 to 26 (21 residues), see Phobius details amino acids 63 to 84 (22 residues), see Phobius details amino acids 138 to 157 (20 residues), see Phobius details amino acids 177 to 197 (21 residues), see Phobius details amino acids 254 to 274 (21 residues), see Phobius details amino acids 285 to 305 (21 residues), see Phobius details amino acids 332 to 352 (21 residues), see Phobius details amino acids 359 to 378 (20 residues), see Phobius details amino acids 384 to 403 (20 residues), see Phobius details amino acids 424 to 443 (20 residues), see Phobius details amino acids 486 to 510 (25 residues), see Phobius details amino acids 531 to 553 (23 residues), see Phobius details TIGR00680: K+-transporting ATPase, A subunit" amino acids 1 to 562 (562 residues), 795.5 bits, see alignment E=1.3e-243 PF03814: KdpA" amino acids 11 to 561 (551 residues), 836.3 bits, see alignment E=4.3e-256

Best Hits

Swiss-Prot: 74% identical to KDPA_METNO: Potassium-transporting ATPase potassium-binding subunit (kdpA) from Methylobacterium nodulans (strain LMG 21967 / CNCM I-2342 / ORS 2060)

KEGG orthology group: K01546, K+-transporting ATPase ATPase A chain [EC: 3.6.3.12] (inferred from 74% identity to mno:Mnod_0193)

MetaCyc: 58% identical to K+ transporting P-type ATPase subunit KdpA (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-2 [EC: 7.2.2.6]

Predicted SEED Role

"Potassium-transporting ATPase A chain (EC 3.6.3.12) (TC 3.A.3.7.1)" in subsystem Potassium homeostasis (EC 3.6.3.12, TC 3.A.3.7.1)

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.12

Use Curated BLAST to search for 3.6.3.12 or 7.2.2.6

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (569 amino acids)

>MPMX19_03745 Potassium-transporting ATPase potassium-binding subunit (Azospirillum sp. SherDot2)
MTVNGWIQILVFLALVVAMTRPLGGFMTRVFTGERTLLSPILGPVERALYRLAGVDERTE
QHWVTYAVSMLLFSAAGMLLLYALQRLQAVLPLNPQDMAAVPADLAFNTAASFTTNTNWQ
NYGGETTMGHLVQMAGLTFHNYVSAATGIALAVALVRGFARTSARTVGNFWVDLTRATLY
VLLPLCVVCALFLVWQGVPQTLAGAVDATTLEGAKQTISLGPVASQEAIKMLGTNGGGFF
NANSAHPFENPNALTNLVEMLCIFALGAGLTNLFGRMVGDERQGWAILAAMGLLFVAGVA
VAYWAEAQGNPAFASFGIDGSAGNMEGKETRFGIAATALFATVTTAASCGAVNAMHDSFM
PLGGMVPMINMMLGEIIVGGVGAGLYGMLLFAIVALFVAGLMVGRTPEYLGKKLEAKEVK
MTMLAILCLPLMMLGFTAVAVVLDTGTASMANAGPHGFSEALYAYVSGAANNGSAFGGLT
GNTPWYNVTLAIAMLVGRFLVIVPMMAIAGSLASKARAPVSAGTFPTHDGLFVGLLVGVI
LIVGGLTFFPALALGPVVEHLAMTAGTLF