Protein Info for MPMX19_03705 in Azospirillum sp. SherDot2

Annotation: L-cystine transport system permease protein YecS

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 221 transmembrane" amino acids 22 to 45 (24 residues), see Phobius details amino acids 69 to 88 (20 residues), see Phobius details amino acids 90 to 107 (18 residues), see Phobius details amino acids 162 to 176 (15 residues), see Phobius details amino acids 191 to 212 (22 residues), see Phobius details TIGR01726: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family" amino acids 14 to 112 (99 residues), 93.6 bits, see alignment E=4.5e-31 PF00528: BPD_transp_1" amino acids 35 to 217 (183 residues), 73.6 bits, see alignment E=8.8e-25

Best Hits

Swiss-Prot: 38% identical to YECS_ECOL6: L-cystine transport system permease protein YecS (yecS) from Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)

KEGG orthology group: K02029, polar amino acid transport system permease protein (inferred from 66% identity to vap:Vapar_5242)

MetaCyc: 38% identical to cystine ABC transporter membrane subunit (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-290 [EC: 7.4.2.12]; 7.4.2.12 [EC: 7.4.2.12]; 7.4.2.- [EC: 7.4.2.12]; 7.4.2.- [EC: 7.4.2.12]; 7.4.2.- [EC: 7.4.2.12]; 7.4.2.- [EC: 7.4.2.12]

Predicted SEED Role

"ABC transporter permease protein"

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.4.2.12

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (221 amino acids)

>MPMX19_03705 L-cystine transport system permease protein YecS (Azospirillum sp. SherDot2)
MSYQWDFSPVLTRWPLLLDGLLNTVKIAAIAIVFGVLVGLVLALLRLSPRRALRLPAAVF
VEFYRNTPPIVHFFWFFYALPVVLNISLDPLIAAVLALSTQSGAFYAEVFRGGIRSIERG
QWEGAKALGMTHTQLMRRIVVPQAATRMVAPFVERSFELIKTTALASTLAYGELLYQAMM
VNSETFRPLEVYTAVALLYLVLLVSCSALSRVAEARLTAYR