Protein Info for MPMX19_03576 in Azospirillum sp. SherDot2

Annotation: Fosmidomycin resistance protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 398 signal peptide" amino acids 1 to 28 (28 residues), see Phobius details transmembrane" amino acids 49 to 72 (24 residues), see Phobius details amino acids 82 to 101 (20 residues), see Phobius details amino acids 107 to 124 (18 residues), see Phobius details amino acids 144 to 165 (22 residues), see Phobius details amino acids 171 to 191 (21 residues), see Phobius details amino acids 221 to 245 (25 residues), see Phobius details amino acids 257 to 276 (20 residues), see Phobius details amino acids 287 to 306 (20 residues), see Phobius details amino acids 312 to 333 (22 residues), see Phobius details amino acids 344 to 366 (23 residues), see Phobius details amino acids 373 to 393 (21 residues), see Phobius details PF07690: MFS_1" amino acids 23 to 359 (337 residues), 131.6 bits, see alignment E=1.7e-42 amino acids 242 to 393 (152 residues), 43.3 bits, see alignment E=1.2e-15

Best Hits

Swiss-Prot: 62% identical to FSR_ECOLI: Fosmidomycin resistance protein (fsr) from Escherichia coli (strain K12)

KEGG orthology group: K08223, MFS transporter, FSR family, fosmidomycin resistance protein (inferred from 68% identity to pde:Pden_4835)

MetaCyc: 62% identical to fosmidomycin efflux pump (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-41

Predicted SEED Role

"Fosmidomycin resistance protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (398 amino acids)

>MPMX19_03576 Fosmidomycin resistance protein (Azospirillum sp. SherDot2)
MTDTTMSRPSAGSTAFSILAAISACHLLNDMIQSLLPAVYPILKDEFGLSFAQLGLLTFV
YQLTASLLQPLVGLFTDRKPMPYSLVFGMGSTLLGLLTLAWAPSFPALLAGGMLLGFGSS
VFHPEASRIARQASGGAHGLAQSLFQVGGNLGSALGPLLAAFIILPRGQGSLSWFAFAAL
AGMVVMVRLGSWQRQNAKPRKAGGPATARHADLPAGQVARAVAILIALIVSKYVYLASIT
SYYIFYLIDRFGLSTGDAQLCLFVFLAAVAAGTVIGGPVGDRIGRKTVIWVSILGILPFT
LALPYVGLTTTVILSAVIGLALASAFPAIVVYAQELLPGRVGMVSGLFFGLAFGVAGIGA
AGLGVVADWKGIGFVYTACSFLPLLGLLTIFLPNVERR