Protein Info for MPMX19_03524 in Azospirillum sp. SherDot2

Annotation: hypothetical protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF01261: AP_endonuc_2
  • amino acids 25 to 266 (242 residues), 146.4 bits, E=2.6e-46
• PF14696: Glyoxalase_5
  • amino acids 287 to 420 (134 residues), 107.3 bits, E=1.5e-34
• PF00903: Glyoxalase
  • amino acids 444 to 565 (122 residues), 24.8 bits, E=5e-09

Best Hits

KEGG orthology group: K00457, 4-hydroxyphenylpyruvate dioxygenase [EC: 1.13.11.27] (inferred from 92% identity to azl:AZL_c01600)

Predicted SEED Role

"4-hydroxyphenylpyruvate dioxygenase (EC 1.13.11.27)" in subsystem Aromatic amino acid degradation or Homogentisate pathway of aromatic compound degradation or Plastoquinone Biosynthesis or Tocopherol Biosynthesis (EC 1.13.11.27)

MetaCyc Pathways

• L-tyrosine degradation I (5/5 steps found)
• plastoquinol-9 biosynthesis I (1/3 steps found)
• superpathway of plastoquinol biosynthesis (2/5 steps found)
• L-phenylalanine degradation IV (mammalian, via side chain) (3/9 steps found)
• vitamin E biosynthesis (tocopherols) (1/7 steps found)

KEGG Metabolic Maps

• Phenylalanine metabolism
• Tyrosine metabolism
• Ubiquinone and menaquinone biosynthesis

Isozymes

Compare fitness of predicted isozymes for: 1.13.11.27

Use Curated BLAST to search for 1.13.11.27

Protein Sequence (643 amino acids)

>MPMX19_03524 hypothetical protein (Azospirillum sp. SherDot2)
MPSSAFTFKKSIATVSLSGTLPEKLEAAAAIGFDGVEIFENDLLTFDGSPADVRRIAEGL
GLEITIFQPFRDFEAMPDPIRARNLDRAERKFDVMQELGTDLVLVCSNVQPAAIDDPARA
AADLAEMAERAQRRDLRVGYEALAWGRHVNRWRQAWDIVQRADHPALGLIVDSFHTLALN
DDPSGIADLPGDRIFFVQLADAPALSMDVLSWSRHFRNFPGQGQLPVRRFLDSVLASGYR
GPLSLEIFNDEFRAAPARLTALDGLRSLIHAEAEAGFGPGLPAPPVCHGVEFLEFAVDAA
ARDKLSALLGSLGFRHAGRHRSKDVDLYRQGGVNLVLNSEEDSAASEHFQMHGPSVCAMA
FTVDDAARTIARAEALRCVLWRERVGDGERRIPALRAPDGTLIYLVDGKEARRSIWEDDF
HLFAEEPVGQESNTPPPHGSPLLGIDHVAQALPFGRMDSFVLFYRTVFGFVPESLWELPD
PYGLIRSRALVSPDAEPGRGVRLPLNISESRRTATGRFVSATSGAGVHHIAFATADADAL
VTDRLAAGAPFLPIPANYYDDLAVKHPLDDATLATLKDRELLYDRDEQGEFLHAYTDSFD
DRFFFEVVERRGGYRQFGAVNAAVRMAVQAQLREGARPELYLD