Protein Info for MPMX19_03398 in Azospirillum sp. SherDot2

Annotation: 5'-deoxyadenosine deaminase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 465 signal peptide" amino acids 1 to 31 (31 residues), see Phobius details TIGR02022: formiminoglutamate deiminase" amino acids 9 to 463 (455 residues), 631.8 bits, see alignment E=3.1e-194 PF01979: Amidohydro_1" amino acids 56 to 439 (384 residues), 114.7 bits, see alignment E=5.7e-37 PF07969: Amidohydro_3" amino acids 231 to 440 (210 residues), 40.9 bits, see alignment E=2e-14

Best Hits

KEGG orthology group: K05603, formimidoylglutamate deiminase [EC: 3.5.3.13] (inferred from 56% identity to pag:PLES_54961)

Predicted SEED Role

"Formiminoglutamic iminohydrolase (EC 3.5.3.13)" in subsystem Histidine Degradation (EC 3.5.3.13)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.5.3.13

Use Curated BLAST to search for 3.5.3.13

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (465 amino acids)

>MPMX19_03398 5'-deoxyadenosine deaminase (Azospirillum sp. SherDot2)
MTAARRLDRLFCDRALLAGGWASGVLLRFDAQGMIAAIETGVDRPPAGVERATGPVIPGM
PNLHSHAFQRAMAGLTERAGPAEDSFWTWREVMYGFVRRIDPDSLQAVATMAYAEMLERG
YTSVAEFHYLHHDADGRRYGDPAEMSMRILAAADATGIGLTHLPVLYAQGGFGGQPAGEG
QRRFLNDPDRLLGIVEACRATPGGHRVGLALHSLRAVSPEAMAAALDGMAALDPTAPIHI
HVAEQTAEVDACLSWSGQRPVEWLLDRGWLGPSWCLVHATHVTAGEVAGIAASRAVAGLC
PTTEADLGDGLFPARDFLAQGGRFGIGSDSQIVIDAAEELRLLEFGQRLAARRRNLLAPH
PDSSTGAALYRAAVTGGAQALGQPEPAGGLKSGQRADLVVLDPDDPRLYGRSDDTLLDSY
VFASARNPVRDVVAAGRLVVRDGRHVDADAIRTGWRRAVDRLHAA