Protein Info for MPMX19_03388 in Azospirillum sp. SherDot2

Annotation: 6-hydroxypseudooxynicotine dehydrogenase complex subunit alpha

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00941: FAD_binding_5
  • amino acids 5 to 174 (170 residues), 163.8 bits, E=3.4e-52

Best Hits

KEGG orthology group: K03519, carbon-monoxide dehydrogenase medium subunit [EC: 1.2.99.2] (inferred from 95% identity to azl:AZL_a11010)

MetaCyc: 61% identical to hmfB (Cupriavidus basilensis)
2-furoyl-CoA dehydrogenase. [EC: 1.3.99.8]

Predicted SEED Role

"Carbon monoxide dehydrogenase medium chain (EC 1.2.99.2)" in subsystem CO Dehydrogenase (EC 1.2.99.2)

MetaCyc Pathways

• furfural degradation (6/8 steps found)
• 5-hydroxymethylfurfural degradation (5/10 steps found)

KEGG Metabolic Maps

• Methane metabolism
• Trinitrotoluene degradation

Isozymes

Compare fitness of predicted isozymes for: 1.2.99.2

Use Curated BLAST to search for 1.2.99.2 or 1.3.99.8

Protein Sequence (278 amino acids)

>MPMX19_03388 6-hydroxypseudooxynicotine dehydrogenase complex subunit alpha (Azospirillum sp. SherDot2)
MKPAPFDYLRPATVADALAALADGGDDARVIAGGQSLLPMLNMRLVQPRLLIDLGRLEEL
RTLRAEDGWLTVGAAVTQAEVLARPTLAREVPLLAAALPWVGHFQTRNRGTLCGSVAHAD
PSAETPLCLVAAGGEVVLRNAKRRRTIAAADFFLGPLTTVKAADEIVECIRFPLARPGCG
HAFREQSMRHGDFAIAACAATVDGDRASLAVGGVADRPTMRSWPLVEGGLPPDLDEALNA
FAWDLGGDDDQHATARYRRDLVRRIGRTVLEEALSCRR