Protein Info for MPMX19_03259 in Azospirillum sp. SherDot2

Annotation: Glycine betaine transport system permease protein OpuAB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 282 transmembrane" amino acids 25 to 66 (42 residues), see Phobius details amino acids 70 to 88 (19 residues), see Phobius details amino acids 94 to 118 (25 residues), see Phobius details amino acids 138 to 164 (27 residues), see Phobius details amino acids 209 to 236 (28 residues), see Phobius details amino acids 249 to 268 (20 residues), see Phobius details PF00528: BPD_transp_1" amino acids 109 to 265 (157 residues), 71.7 bits, see alignment E=3.4e-24

Best Hits

Swiss-Prot: 42% identical to OPUAB_BACSU: Glycine betaine transport system permease protein OpuAB (opuAB) from Bacillus subtilis (strain 168)

KEGG orthology group: K02001, glycine betaine/proline transport system permease protein (inferred from 71% identity to ara:Arad_8150)

Predicted SEED Role

"L-proline glycine betaine ABC transport system permease protein ProW (TC 3.A.1.12.1)" in subsystem Choline and Betaine Uptake and Betaine Biosynthesis (TC 3.A.1.12.1)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (282 amino acids)

>MPMX19_03259 Glycine betaine transport system permease protein OpuAB (Azospirillum sp. SherDot2)
MNGNVIISPGAWLAPAVDWLNMNFRPLFAFIGLVIESTLGGINALLLSMPPYALVALSVV
FALLLANRRIAVLVAAAMGFCYIAGLWQATVQTVTLVTISVVISVAIAFPLGVVASRVRM
VEAGLRPLLDVMQTVPPWVYLIPAVIVFSLGSVPAIIATVIYGVPPMLRLTTLAFKQVPK
DLLELGQAIGATRQAILFKIELPAAMPTLLVGLNQCILLSLAMVVLAGLVGAGGLGAEVT
RGLTRMEMGVGLRAGLAIVAVAIVLDRLSRGAILRYRTAKAG