Protein Info for MPMX19_02968 in Azospirillum sp. SherDot2

Annotation: multidrug efflux RND transporter permease subunit OqxB28

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1062 transmembrane" amino acids 12 to 31 (20 residues), see Phobius details amino acids 342 to 362 (21 residues), see Phobius details amino acids 369 to 391 (23 residues), see Phobius details amino acids 397 to 419 (23 residues), see Phobius details amino acids 440 to 461 (22 residues), see Phobius details amino acids 472 to 499 (28 residues), see Phobius details amino acids 547 to 567 (21 residues), see Phobius details amino acids 880 to 898 (19 residues), see Phobius details amino acids 905 to 927 (23 residues), see Phobius details amino acids 933 to 956 (24 residues), see Phobius details amino acids 979 to 1000 (22 residues), see Phobius details amino acids 1010 to 1036 (27 residues), see Phobius details PF00873: ACR_tran" amino acids 3 to 1036 (1034 residues), 1186.7 bits, see alignment E=0 TIGR00915: RND transporter, hydrophobe/amphiphile efflux-1 (HAE1) family" amino acids 4 to 1043 (1040 residues), 1180 bits, see alignment E=0 PF03176: MMPL" amino acids 294 to 501 (208 residues), 41.1 bits, see alignment E=1.1e-14 amino acids 886 to 1036 (151 residues), 25.1 bits, see alignment E=8.3e-10

Best Hits

KEGG orthology group: None (inferred from 97% identity to azl:AZL_b06270)

Predicted SEED Role

"RND efflux system, inner membrane transporter CmeB" in subsystem Multidrug Resistance Efflux Pumps or Multidrug efflux pump in Campylobacter jejuni (CmeABC operon)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1062 amino acids)

>MPMX19_02968 multidrug efflux RND transporter permease subunit OqxB28 (Azospirillum sp. SherDot2)
MNISKFFIDRPIFAGVLSVALFLAGAIAVFRLPISEYPEVVPPSVVVRAQFPGANPKVIA
ETVASPLEEQINGVEGMLYMQSQANSDGNLALTVTFKLGTDPDKAQQLVQNRVAQAMPRL
PSDVQRLGVATVKSSPTLTMVVHLLSPNDRYDMTYLRNYAVLNVKDRLTRISGVGEVQVW
GAGDYAMRVWLDPGKVAQRGLTATDVVNSIREQNVQVAAGVIGASPSLPDVPMQLSINAR
GRLKTADEFGDIVLKTGGEGGVTRLRDVARVELAAAQYGLRSLLDNKPAVALGITQTPDA
NALAISDEVRKVMAELKGDMPDGVDYSIVYDPTQFVRSSIEAVVHTLLEAVALVVLVVIV
FLQTWRASIIPLLAVPISIVGTFSLLLAFGFSINALSLFGMVLAIGIVVDDAIVVVENVE
RNIASGLSARDATIRAMQEVSGPIIAIALTLVAVFVPLAAMTGLTGEFYKQFAMTIAIST
VISAFNSLTLSPALAAVLLRGHDEPQDWLTRAMNRVFGGFFRLFNRVFHRASEGYGRGVG
GVVRRKGVMLAVYALLIGATVLLGRSVPSGFVPMQDKEYLISFAQLPNGASLDRTEAVIR
EMTDIALKRPGVQSAVAFPGLSVNGFTNSSSAGIVFVTLKPFAERKDPSLSAGAIAMDLQ
QRYAGLKEAFVAIFPPPPVMGLGQLGGFKMQLEDRGNLGYEALSDAVNAFVKRAAQTPEL
GPTFSAYQINVPQLDVDLDRVKAKQLGVNVADVFDTMQIYLGSLYVNDFNAFGRVYQVRV
QADAPFRDTADDIGVLKTRNAAGTMVPLSSLVTVQPGYGPEMVVRYNGFTAADVNGGPAP
GFSSGQAEAAAERIAAEVLPRGVKLEWTDLTYQKILVGNAGLWVFPISVLLVFLVLAAQY
ESLTLPLAILLIVPMSVLSALFGVWLTGGDNNIFTQIGFMVLVGLSAKNAILIVEFAREL
EHEGRGVVQAAIEASRLRLRPILMTSIAFIMGVVPLVTSSGAGAEMRHAMGVAVFAGMIG
VTLFGLVLTPVFYVLLRKLAGAERRVDAPAEGGVQPAEWKMG