Protein Info for MPMX19_02888 in Azospirillum sp. SherDot2

Annotation: 6-phosphogluconolactonase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF10282: Lactonase
  • amino acids 63 to 362 (300 residues), 286.1 bits, E=4.1e-89

Best Hits

Swiss-Prot: 44% identical to 6PGL_PECCP: 6-phosphogluconolactonase (pgl) from Pectobacterium carotovorum subsp. carotovorum (strain PC1)

KEGG orthology group: K07404, 6-phosphogluconolactonase [EC: 3.1.1.31] (inferred from 61% identity to bra:BRADO5790)

Predicted SEED Role

"6-phosphogluconolactonase (EC 3.1.1.31)" in subsystem Entner-Doudoroff Pathway or Pentose phosphate pathway (EC 3.1.1.31)

MetaCyc Pathways

• superpathway of glucose and xylose degradation (15/17 steps found)
• superpathway of glycolysis and the Entner-Doudoroff pathway (15/17 steps found)
• Entner-Doudoroff pathway I (9/9 steps found)
• heterolactic fermentation (15/18 steps found)
• pentose phosphate pathway (7/8 steps found)
• pentose phosphate pathway (oxidative branch) I (2/3 steps found)
• formaldehyde oxidation I (3/6 steps found)

KEGG Metabolic Maps

• Biosynthesis of alkaloids derived from histidine and purine
• Biosynthesis of plant hormones
• Pentose phosphate pathway

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.1.1.31

Protein Sequence (366 amino acids)

>MPMX19_02888 6-phosphogluconolactonase (Azospirillum sp. SherDot2)
MGRRYGIALAMLLTSAAFVGAVPAQADSFAYVSNAGSNDISVFRLDGNSGAMTPVGTAPF
VGVDKPGSSTPLALSPDRRFLYAGVRSQPYQVQIFAIDAATGKLSHLGSGPLADSMANIV
TDRSGKYLFSASYGGDKVAVNPIGPDGKVGPPQQVVATGKNAHSIQPSPDNRFAFATNLG
SDRLVQFRFDAATGGLSENDPPSVALPAKSGPRHIVFHPDGRHLYLVDELDAAVAVFAYD
PATGRLTETQRLPSLPADFKGEPWAADIHTTPDGRFLYISERRTSTIRSFRIDPESRQLT
PLASVATEEQPRGFNIDPTGRFLAAVGEKSDGMTVYRIDGGSGALTTLARYPAGKQPNWV
EFVAAP