Protein Info for MPMX19_02821 in Azospirillum sp. SherDot2

Annotation: Sensor histidine kinase RcsC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1072 transmembrane" amino acids 223 to 241 (19 residues), see Phobius details PF08448: PAS_4" amino acids 19 to 114 (96 residues), 36.8 bits, see alignment E=2.1e-12 amino acids 307 to 418 (112 residues), 32.3 bits, see alignment E=5e-11 amino acids 584 to 682 (99 residues), 30.5 bits, see alignment E=1.8e-10 PF01590: GAF" amino acids 142 to 278 (137 residues), 49.5 bits, see alignment E=3.3e-16 PF13185: GAF_2" amino acids 143 to 280 (138 residues), 33.6 bits, see alignment E=2.1e-11 PF08447: PAS_3" amino acids 454 to 531 (78 residues), 31.4 bits, see alignment 9.1e-11 amino acids 597 to 665 (69 residues), 52.7 bits, see alignment 2.2e-17 TIGR00229: PAS domain S-box protein" amino acids 572 to 687 (116 residues), 59.3 bits, see alignment E=2e-20 PF00989: PAS" amino acids 573 to 665 (93 residues), 28.3 bits, see alignment E=7.7e-10 PF13426: PAS_9" amino acids 583 to 679 (97 residues), 28.7 bits, see alignment E=6.9e-10 PF02518: HATPase_c" amino acids 809 to 929 (121 residues), 68.3 bits, see alignment E=3.8e-22 PF00072: Response_reg" amino acids 954 to 1059 (106 residues), 48.2 bits, see alignment E=5.5e-16

Best Hits

Predicted SEED Role

"Sensory box histidine kinase/response regulator"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1072 amino acids)

>MPMX19_02821 Sensor histidine kinase RcsC (Azospirillum sp. SherDot2)
MVGLMMRSRQAMFIGWGPDVTVLYNDAYRDILGSRHPAALGRPMSEVWPDAWPQVRDFVR
RAYEGESLLHEDLLVPLERRGLGEDYYFTFSYTPIAGETGCIGGFLCIVAETTLAVRGRR
RMAFHAELEHRLRELTNPLCVVTVAAEALGRHLDASRVGYGVMDESERFFTTERNWTDGT
VAPHIGTHDLLVFGEPVLATLRRGQSLVVDDAATDPRTATPDLLAAFAAFGFSSVVTASL
VKQGRMVAALYVHDRRSRHWREDEIELIEEVAERTWSAVERVQAEEEVRRANERLRAEGE
RLRALFRQAPGFMYVWRGPDHVFEMANDAYFELIGRRDVIGKPGREALPEIVGQGFFELA
DRVYRTGEPFVGEGMPARIARRPGTPLEERFVTFVFQPIRDDEGQVTGLFVQGSDVTGMK
RTEEALRESEQRLHIAQDAGGVGTFELRADGLLAVSPQFCRLWGIDERPLVRLEELVGLI
HPEDRPTLNTLQPGQVPTDGLGYVEYRILRPDTGAVRWIARRAQAFKRDEDADGGGVRVL
GACYDITDRRCAEDALRALNATLEQRVAERTADRDRMWRLSTDIMLVARFDGTIGAVNPA
WTTLLGWREEDLQGAVFLDFVHPDDLDATVAEVGRLRTGLTTLRFENRYRHKDGSYRWIS
WTAVPDDRFIHAVGRDVTARKEAAAALRRAEDQLRQAQKMEAVGQLTGGVAHDFNNLLQA
LSSCLTMIGRRSAEPRLAPLLEAGMQAVDRGAKLVQQLMGFARRDSLRPEPIDVRDRVLG
MAGLLERALRADIRLETRFAPGLHPIEVDPTQFELALINMAVNARDAMLGGGTLTVEAEN
RTLGPGETTGLDGGGLEGEFLRLTVADTGTGMPPEVVARAFDPFFTTKEVGKGSGLGLAQ
VYGLARQAGGTVWIESRPGEGTRIVLLLRAGTGIPRASAAPAQAAAGLVRGARVLMVEDD
PVVASSVAAALEESGWTVLRAASADEALPLLAGDERIDLLFSDVVMPGRLSGIDLGREAA
LLRPGLPVVLTTGYSEDVARTEGIAVLSKPYRIDTLLQTLSEALAKKPSSQR