Protein Info for MPMX19_02756 in Azospirillum sp. SherDot2

Annotation: Glutathione transport system permease protein GsiC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 316 transmembrane" amino acids 9 to 30 (22 residues), see Phobius details amino acids 99 to 121 (23 residues), see Phobius details amino acids 132 to 159 (28 residues), see Phobius details amino acids 173 to 194 (22 residues), see Phobius details amino acids 234 to 257 (24 residues), see Phobius details amino acids 280 to 306 (27 residues), see Phobius details PF19300: BPD_transp_1_N" amino acids 1 to 88 (88 residues), 57.3 bits, see alignment E=1.8e-19 PF00528: BPD_transp_1" amino acids 113 to 311 (199 residues), 133.5 bits, see alignment E=7.4e-43

Best Hits

Swiss-Prot: 44% identical to Y1092_BRUSU: Putative peptide transport system permease protein BRA1092/BS1330_II1084 (BRA1092) from Brucella suis biovar 1 (strain 1330)

KEGG orthology group: K02033, peptide/nickel transport system permease protein (inferred from 92% identity to azl:AZL_026820)

MetaCyc: 36% identical to murein tripeptide ABC transporter / oligopeptide ABC transporter inner membrane subunit OppB (Escherichia coli K-12 substr. MG1655)
3.6.3.23-RXN [EC: 7.4.2.6]; 7.4.2.6 [EC: 7.4.2.6]

Predicted SEED Role

"Dipeptide transport system permease protein DppB (TC 3.A.1.5.2)" in subsystem ABC transporter dipeptide (TC 3.A.1.5.2) (TC 3.A.1.5.2)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.4.2.6

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (316 amino acids)

>MPMX19_02756 Glutathione transport system permease protein GsiC (Azospirillum sp. SherDot2)
MLAFLLRRLVSLTVTVWLATIVVFTVLQLVPGDPALLMLGIDAQPDTLAVLRSQMGLDQP
ILTRYLHWAGGLARGDLGVSLTYARPVADLVAERLAVTLPLSLLSLVLSTMLALPLGLLA
AARRGRGGDWAVLGFAQLGVSMPSFWIAILLILLFSLTLHWFPAGGFPGWSAGIGPALQA
LVLPALALAVPEAAILARVTRTAVLDTLGEDHIRTARAKGVGRMAVLLRHALPNALIPVA
TVLGLQISFLVAGAVVVENVFTLPGLGRLLYQAIGQRDLIVVQGVVVLLALFVVLVNALV
DIACALADPRPKGGAS