Protein Info for MPMX19_02672 in Azospirillum sp. SherDot2
Annotation: Ubiquinone biosynthesis O-methyltransferase
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 60% identical to UBIG_PARL1: Ubiquinone biosynthesis O-methyltransferase (ubiG) from Parvibaculum lavamentivorans (strain DS-1 / DSM 13023 / NCIMB 13966)
KEGG orthology group: K00568, 3-demethylubiquinone-9 3-methyltransferase [EC: 2.1.1.- 2.1.1.64] (inferred from 94% identity to azl:AZL_001130)MetaCyc: 56% identical to 2-polyprenyl-6-hydroxyphenol methylase (Cereibacter sphaeroides)
3-demethylubiquinone-9 3-O-methyltransferase. [EC: 2.1.1.64]; RXN-9233 [EC: 2.1.1.64, 2.1.1.222]
Predicted SEED Role
"3-demethylubiquinone-9 3-methyltransferase (EC 2.1.1.64)" in subsystem Ubiquinone Biosynthesis (EC 2.1.1.64)
MetaCyc Pathways
- superpathway of ubiquinol-8 biosynthesis (early decarboxylation) (7/12 steps found)
- ubiquinol-10 biosynthesis (early decarboxylation) (4/8 steps found)
- ubiquinol-8 biosynthesis (early decarboxylation) (4/8 steps found)
- ubiquinol-9 biosynthesis (early decarboxylation) (3/8 steps found)
- ubiquinol-9 biosynthesis (late decarboxylation) (3/8 steps found)
- ubiquinol-10 biosynthesis (late decarboxylation) (3/9 steps found)
- ubiquinol-6 biosynthesis (late decarboxylation) (2/8 steps found)
- ubiquinol-7 biosynthesis (early decarboxylation) (2/8 steps found)
- ubiquinol-7 biosynthesis (late decarboxylation) (2/8 steps found)
- superpathway of chorismate metabolism (38/59 steps found)
- ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast) (2/9 steps found)
- ubiquinol-8 biosynthesis (late decarboxylation) (2/9 steps found)
- superpathway of ubiquinol-6 biosynthesis (late decarboxylation) (3/11 steps found)
KEGG Metabolic Maps
- Alkaloid biosynthesis I
- Anthocyanin biosynthesis
- Benzoxazinone biosynthesis
- Biosynthesis of alkaloids derived from shikimate pathway
- Carotenoid biosynthesis - General
- Flavonoid biosynthesis
- Histidine metabolism
- Insect hormone biosynthesis
- Naphthalene and anthracene degradation
- Phenylpropanoid biosynthesis
- Porphyrin and chlorophyll metabolism
- Tryptophan metabolism
- Tyrosine metabolism
- Ubiquinone and menaquinone biosynthesis
Isozymes
Compare fitness of predicted isozymes for: 2.1.1.-, 2.1.1.64
Use Curated BLAST to search for 2.1.1.- or 2.1.1.222 or 2.1.1.64
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (264 amino acids)
>MPMX19_02672 Ubiquinone biosynthesis O-methyltransferase (Azospirillum sp. SherDot2) MTASSSAFPHASATAANGGMAGGTVDPEDVARFSAIAAEWWDPAGKFKPLHRLNPLRLTY IRDAVCKRLGRDPLAPNPLAGLRIVDIGCGGGLLAEPLARMGATVVGVDASEKNIKTAAT HAAETGTTVDYRATTAEALAASGETFDVVLAMEVIEHVADVPLFVKSLSDLLAPGGALFL ATLNRTPKSFALAIVGAEYILRWLPRGTHNWRQFLRPSELNAIVRPYGLSVRDLTGITYN PLSDEFRLNARDLDVNYMGWAERG