Protein Info for MPMX19_02619 in Azospirillum sp. SherDot2

Annotation: Adaptive-response sensory-kinase SasA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 569 transmembrane" amino acids 21 to 43 (23 residues), see Phobius details amino acids 248 to 268 (21 residues), see Phobius details PF13755: Sensor_TM1" amino acids 18 to 69 (52 residues), 49.3 bits, see alignment 8.3e-17 PF13756: Stimulus_sens_1" amino acids 94 to 205 (112 residues), 99.1 bits, see alignment E=5.9e-32 PF00672: HAMP" amino acids 266 to 319 (54 residues), 36.7 bits, see alignment 1.1e-12 PF00512: HisKA" amino acids 326 to 389 (64 residues), 50.1 bits, see alignment E=5.8e-17 PF02518: HATPase_c" amino acids 455 to 568 (114 residues), 79.9 bits, see alignment E=4.9e-26

Best Hits

KEGG orthology group: K14980, two-component system, OmpR family, sensor histidine kinase ChvG [EC: 2.7.13.3] (inferred from 90% identity to azl:AZL_000650)

Predicted SEED Role

"Sensor histidine kinase ChvG (EC 2.7.3.-)" (EC 2.7.3.-)

Isozymes

Compare fitness of predicted isozymes for: 2.7.13.3, 2.7.3.-

Use Curated BLAST to search for 2.7.13.3 or 2.7.3.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (569 amino acids)

>MPMX19_02619 Adaptive-response sensory-kinase SasA (Azospirillum sp. SherDot2)
MSTLGGAGGGRRRRLGGVSPLTLRILAVNVLALLVLLAGLLYLGRYQDRLIQAETEALAT
EARIFASALGEGAVNRILTAPSPTGDESGERFELAPELARPMIRRLAEATSTRTRLFDID
GHMLSDSRVLVGSQGRIEIRELPTPPSGDPVSRAINDLYTRLIDVVPSREGLPVYREQPG
QPNPDVERALVGEAAATVWRVDGAGGDPELLLTVAVPVQRYREVLGAVLLTRGGGEIDRA
IRSVRFDILRVFGVALLVTIGLSFYLAGTIARPIRRLAQAADRLRTSHGRHAEIPDLTRR
GDEIGELSGVLREMTDALWTRMDAIERFAADVAHEIKNPLTSLRSAVETAERVSDPRHRD
RLMAIIADDVQRLDRLISDISNASRLDAELSRAEPEPVDIGLLLTMLAELRQTVAATMDE
RVAAGDGEDGGTRLRPPRVVLDLPAAERLVVPGLEGRLTQVFQNLIDNALSFSPPGGTVR
LTARRSGPSVKVVVSDQGPGIPDGKEEAIFDRFYTERPAGEKFGTHSGLGLSIAKQIVSA
HNGSVFAKNRYVSDGTIEGADFVVTLPLL