Protein Info for MPMX19_02582 in Azospirillum sp. SherDot2

Annotation: Alkaline phosphatase synthesis sensor protein PhoR

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 544 signal peptide" amino acids 9 to 11 (3 residues), see Phobius details transmembrane" amino acids 12 to 30 (19 residues), see Phobius details amino acids 37 to 55 (19 residues), see Phobius details PF00512: HisKA" amino acids 248 to 312 (65 residues), 72.2 bits, see alignment E=4.3e-24 PF02518: HATPase_c" amino acids 360 to 496 (137 residues), 88 bits, see alignment E=9e-29

Best Hits

KEGG orthology group: K07636, two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC: 2.7.13.3] (inferred from 92% identity to azl:AZL_000230)

Predicted SEED Role

"Phosphate regulon sensor protein PhoR (SphS) (EC 2.7.13.3)" in subsystem High affinity phosphate transporter and control of PHO regulon or Phosphate metabolism (EC 2.7.13.3)

Isozymes

Compare fitness of predicted isozymes for: 2.7.13.3

Use Curated BLAST to search for 2.7.13.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (544 amino acids)

>MPMX19_02582 Alkaline phosphatase synthesis sensor protein PhoR (Azospirillum sp. SherDot2)
MRQKASPPTPLLTAILLMLAPLAGVLTWAVYSGALHGGLALAAGVAALAGAVQILRTYRR
DANAVTDYAARLAETDEPLAPAGTPPALKALAATIGRLHRVGLRRAESVRMQLDADEAVI
DALPAPLLLMDADRQVVRANQTARELFGDKIVDRDLASSLRTPAVLEAVDSVLRGGASRI
IEFTLPVPVERSFEAQVKPFQRLVPEPDPSLLDGEIEEEPAPRPPTVARMAILTLHDVTA
ARRSEQMRADFIANASHELRTPLSSLLGFIETLRGPARDDPEAQDRFLAIMHDQASRMTR
LVNDLLSLSRIELDEHMQPNGRVDVVEELENVIAALQLKAAERRIRLRMEAPEDLPPVVG
DEDQLTQVFQNLVSNAIKYTREDTDVTVSVALADGAAVGFTGLPAPGAAAKDKRVGRGGT
AMVSVSVRDRGDGIARTHLPRLTERFYRVDAARSRAMGGTGLGLAIVKHILNRHRGRLTI
ESEVGVGSAFTVYLPAVGETVSPSLPRGEGRGEGETRQDFRGRAAALPPHPNPLPGGERG
YGGV