Protein Info for MPMX19_02520 in Azospirillum sp. SherDot2

Annotation: Transcription termination/antitermination protein NusA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 523 PF08529: NusA_N" amino acids 2 to 122 (121 residues), 134.9 bits, see alignment E=4e-43 TIGR01953: transcription termination factor NusA" amino acids 2 to 339 (338 residues), 447.4 bits, see alignment E=3.1e-138 PF00575: S1" amino acids 129 to 190 (62 residues), 25.2 bits, see alignment E=4.4e-09 PF13184: KH_5" amino acids 227 to 293 (67 residues), 92.7 bits, see alignment E=3.1e-30 TIGR01954: transcription termination factor NusA, C-terminal duplication" amino acids 362 to 409 (48 residues), 60 bits, see alignment 1.9e-20 PF14520: HHH_5" amino acids 363 to 406 (44 residues), 22.5 bits, see alignment 3.2e-08

Best Hits

Swiss-Prot: 51% identical to NUSA_RICCN: Transcription termination/antitermination protein NusA (nusA) from Rickettsia conorii (strain ATCC VR-613 / Malish 7)

KEGG orthology group: K02600, N utilization substance protein A (inferred from 94% identity to azl:AZL_028570)

Predicted SEED Role

"Transcription termination protein NusA" in subsystem NusA-TFII Cluster or Transcription factors bacterial

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (523 amino acids)

>MPMX19_02520 Transcription termination/antitermination protein NusA (Azospirillum sp. SherDot2)
MELLQVADAVAREKNIDRDEVLEAMEQAIQKAGRSKYGHEHDIRARIDRKTGDIHLTRHL
EVVETVENEATQVTLPYAQKRKAGAKLGDFLVDPLPPIDFGRIAAQTAKQVIVQKVRDAE
RKRQFNEYKDRNGEIVNGLVKRVEYGNVTVDLGRAEAILRRDELLPREHFKNGDRVRAYI
FDVREEPRGPQIFLSRTHPMFMAKLFAQEVPEIYDGIIEIKAVARDPGSRAKIAVLSHDS
SIDPVGACVGMRGSRVQAVVGELQGEKIDIIPWNGEAPTFVVNALAPAEVAKVVLDDDNH
RIEVVVPDDQLSLAIGRRGQNVRLASMLTGWDIDILTEQEESERRSEEIHNRSALFMQAL
DVDDVIAHLLVAEGFTSVEEIAYVETEELAEIEGFDESVADELKQRALAFLEVRDEQANE
RRLELGVEDIIAELTGFSATQLVKLGENGVKTLDDLADLAGDELVEILGKDGAKDAPSEE
EANAIIMAARAHWFEGEGEDGAAAAPAADGAAAGSADGHGAQA