Protein Info for MPMX19_02484 in Azospirillum sp. SherDot2

Annotation: Heat-inducible transcription repressor HrcA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 346 TIGR00331: heat-inducible transcription repressor HrcA" amino acids 7 to 344 (338 residues), 326.2 bits, see alignment E=1.6e-101 PF01628: HrcA" amino acids 108 to 331 (224 residues), 210.3 bits, see alignment E=1.7e-66

Best Hits

Swiss-Prot: 58% identical to HRCA_RHOPT: Heat-inducible transcription repressor HrcA (hrcA) from Rhodopseudomonas palustris (strain TIE-1)

KEGG orthology group: K03705, heat-inducible transcriptional repressor (inferred from 99% identity to azl:AZL_028240)

Predicted SEED Role

"Heat-inducible transcription repressor HrcA" in subsystem Heat shock dnaK gene cluster extended

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (346 amino acids)

>MPMX19_02484 Heat-inducible transcription repressor HrcA (Azospirillum sp. SherDot2)
MINELNQRSREIFRLIVDAYVASGEPVGSRTISRRLGMALSPATIRNVMADLEEQGLLYA
PHTSAGRIPTDAGLRMFVDGLLEIGSLTEDERASIEAKCSASGRAFADVLGEASTMLSGL
SHCAGLVVAPKTDRPLKHIEFVSLGPGRALVVLVNEDGLVENRVIEVPMGVPTSTLQTVS
NFLSAKLAGRTLDEARQEVLQEIEQQKTQLDELSRKVVAAGLATWAGSGGSNAGQLIVRG
QSRLLEDVTALSDLERVRGLFEALETKETMLRMLDATGRGDGVQIFIGAENVLFSHSGCS
MIISPFQNSREQVIGAIGVIGPTRINYARIIPLVDYTAKVVSRLIG